Cluster of Excellence –
University of Freiburg

Prof. Dr. Michael Reth

Prof. Dr. Michael Reth

Institute of Biology III (Molecular Immunology), University of Freiburg

+49 761 203 2718

 

10 Selected publications:

  • Continuous signalling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells.
    He X, Kläsener K, Iype JM, Becker M, Maity PC, Cavallari M, Nielsen PJ, Yang, J, Reth, M (2018).
    EMBO J. 37(11) doi: 10.15252/embj.201797980.
  • The BTG2-PRMT2 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex.
    Dolezal E, Infantino S, Drepper F, Börsig T, Singh A, Wossning T, Fiala GJ, Minguet S, Warscheid B, Tarlinton DM, Jumaa H, Medgeysi D, Reth M (2017).
    Nat Immunol 18(8): 911-920.
  • Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance.
    Minguet S, Kläsener K, Schaffer AM, Fiala GJ, Osteso-Ibánez T, Raute K, Navarro-Lérida I, Hartl FA, Seidl M, Reth M, Del Poszo, MA (2017).
    Nat Immunol 18 (10): 1150-1159.
  • Molecular requirements of the B cell antigen receptor for sensing monovalent antigens.
    Volkmann C, Brings N, Becker M, Hobeika E, Yang J, Reth M. (2016).
    EMBO J. 35 (21):2371-2381.
  • B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk.
    Kläsener K, Maity PC, Hobeika E, Yang J, Reth M. (2014).
    Elife 3: e02069.
  • Pillars of Immunology article.
    Reth M. (2014).
    J Immunol 192(9):415-416. Reprint of “Antigen receptor tail clue”. Nature (1989).338:383-384.
  • Matching cellular dimensions with molecular sizes.
    Reth M.
    Nat Immunol. 2013 Aug;14(8):765-7.
  • Oligomeric organization of the B-cell antigen receptor on resting cells.
    Yang J, Reth M (2010).
    Nature 467(7314): 465-469.
  • Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia.
    Jumaa H, Bossaller L, Portugal K, Storch B, Lotz M, Flemming A, Schrappe M, Postila V, Riikonen P, Pelkonen J, Niemeyer CM, Reth M (2003).
    Nature 423, 452-456.
  • Molecular components of the B-cell antigen receptor complex of the IgM class.
    Hombach J, Tsubata T, Leclercq L, Stappert H, Reth M (1990).
    Nature 343: 760-762.
    Reprinted as Pillars of Immunology in J Immunol (2009) 183: 1505-1507