Cluster of Excellence –
University of Freiburg

Prof. Dr. Ralf Baumeister

Prof. Dr. Ralf Baumeister

Institute of Biology III (Bioinformatics and Molecular Genetics), University of Freiburg

+49 761 203 2799


10 selected publications:

  • C. elegans DAF-16/FOXO interacts with TGF-ß/BMP signaling to induce germline tumor formation via mTORC1 activation.
    Qi W, Yan Y, Pfeifer D, Donner V Gromoff E, Wang Y, Maier W, Baumeister R (2017).
    PLoS Genet. 13(5):e1006801
  • TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition.
    Thien A, Prentzell MT, Holzwarth B, Kläsener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K (2015).
    Dev Cell. 32(5):617-30.
  • Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells.
    Thedieck K, Holzwarth B, Prentzell MT, Boehlke C, Kläsener K, Ruf S, Sonntag AG, Maerz L, Grellscheid SN, Kremmer E, Nitschke R, Kuehn EW, Jonker JW, Groen AK, Reth M, Hall MN, Baumeister R (2013). Cell. 154(4):859-74
  • Surveillance-activated defenses block the ROS-induced mitochondrial unfolded protein response.
    Runkel ED, Liu S, Baumeister R, Schulze E (2013).
    PLoS Genet. 9(3):e1003346
  • Cell-nonautonomous signaling of FOXO/DAF-16 to the stem cells of Caenorhabditis elegans.
    Qi W, Huang X, Neumann-Haefelin E, Schulze E, Baumeister R (2012).
    PLoS Genet. 8(8):e1002836.
  • Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity.
    Fatouros C, Pir GJ, Biernat J, Koushika SP, Mandelkow E, Mandelkow EM, Schmidt E, Baumeister R (2012).
    Hum Mol Genet. 21(16):3587-603.
  • SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans.
    Neumann-Haefelin E, Qi W, Finkbeiner E, Walz G, Baumeister R, Hertweck M (2008).
    Genes Dev. 22(19):2721-35.
  • Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans.
    Tullet JM, Hertweck M, An JH, Baker J, Hwang JY, Liu S, Oliveira RP, Baumeister R, Blackwell TK (2008).
    Cell. 132(6):1025-38
  • A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress.
    Springer W, Hoppe T, Schmidt E, Baumeister R (2005).
    Hum Mol Genet. 14(22):3407-23.
  • Regulation of the myosin-directed chaperone UNC-45 by a novel E3/E4-multiubiquitylation complex in C. elegans.
    Hoppe T, Cassata G, Barral JM, Springer W, Hutagalung AH, Epstein HF, Baumeister R (2004).
    Cell. ;118(3):337-49.