Cluster of Excellence –
University of Freiburg

Prof. Dr. Gerd Walz

Prof. Dr. Gerd Walz

Department of Medicine, Renal Division, University Medical Centre Freiburg

+49 761 270 32500

10 selected publications:

  • Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
    Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS (2016).
    Nat Cell Biol. 18, 1269-1280.
  • FAT1 mutations cause a glomerulotubular nephropathy.
    Gee HY, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J, Fang H, Airik R, Vega-Warner V, Cho KJ, Chan TA, Morris LG, ffrench-Constant C, Allen N, McNeill H, Büscher R, Kyrieleis H, Wallot M, Gaspert A, Kistler T, Milford DV, Saleem MA, Keng WT, Alexander SI, Valentini RP, Licht C, Teh JC, Bogdanovic R, Koziell A, Bierzynska A, Soliman NA, Otto EA, Lifton RP, Holzman LB, Sibinga NE, Walz G, Tufro A, Hildebrandt F (2016).
    Nat Commun. 7, 10822.
  • The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells.
    Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G (2015).
    J Cell Biol. 211, 963-73.
  • TSC1 activates TGF-beta-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition.
    Thien A, Prentzell MT, Holzwarth B, Klasener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K (2015).
    Dev Cell 32, 617-630.
  • Autosomal dominant polycystic kidney disease: the changing face of clinical management.
    Ong AC, Devuyst O, Knebelmann B, Walz G (2015).
    Lancet 385, 1993-2002.
  • ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
    Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS (2013).
    Nat Genet. 45, 951-6.
  • Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension.
    Lienkamp SS, Liu K, Karner CM, Carroll TJ, Ronneberger O, Wallingford JB, Walz G (2012).
    Nat Genet. 44, 1382-7.
  • Everolimus in patients with autosomal dominant polycystic kidney disease.
    Walz G, Budde K, Mannaa M, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hörl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Büchert M, May C, Gschaidmeier H, Kramer S, Eckardt KU (2010).
    N Engl J Med. 363, 830-40.
  • Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development.
    Skouloudaki K, Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B, Engel C, Moeller MJ, Englert C, Bollig F, Schafer T, Ramachandran H, Mlodzik M, Huber TB, Kuehn EW, Kim E, Kramer-Zucker A, Walz G (2009).
    Proc Natl Acad Sci U S A 106, 8579-8584.
  • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways.
    Simons M, Gloy J, Ganner A, Bullerkotte A, Bashkurov M, Krönig C, Schermer B, Benzing T, Cabello OA, Jenny A, Mlodzik M, Polok B, Driever W, Obara T, Walz G (2005).
    Nat Genet. 37, 537-43.