Centre for Biological Signalling Studies

Dr. Claudia Jessen-Trefzer

Dr. Claudia Jessen-Trefzer

Pharmaceutical Biology and Biotechnology, University of Freiburg

+49 761 203 8381

10 selected publications:

  1. Artificial metalloenzymes in a nutshell: the quartet for efficient catalysis.
    Ebensperger P, Jessen-Trefzer C.
    Biol Chem. 2021 Oct 18. doi: 10.1515/hsz-2021-0329. Online ahead of print.
  2. Inside a Shell-Organometallic Catalysis Inside Encapsulin Nanoreactors.
    Lohner P, Zmyslia M, Thurn J, Pape JK, Gerasimaitė R, Keller-Findeisen J, Groeer S, Deuringer B, Süss R, Walther A, Hell SW, Lukinavičius G, Hugel T, Jessen-Trefzer C.
    Angew Chem Int Ed Engl. 2021 Oct 25;60(44):23835-23841.
  3. Pyridinium Modified Anthracenes and Their Endoperoxides Provide a Tunable Scaffold with Activity against Gram-Positive and Gram-Negative Bacteria.
    Wang X, Bittner T, Milanov M, Kaul L, Mundinger S, Koch HG, Jessen-Trefzer C, Jessen HJ.
    ACS Infect Dis. 2021 Aug 13;7(8):2073-2080.
  4. The two-component locus MSMEG_0244/0246 together with MSMEG_0243 affects biofilm assembly in M. smegmatis correlating with changes in phosphatidylinositol mannosides acylation.
    Li M, Gašparovič H, Weng X, Chen S, Korduláková J*, Jessen-Trefzer C*
    Frontiers in Microbiology, 2020, doi: 10.3389/fmicb.2020.570606.
    *corresponding author
  5. Understanding the Mechanism of Action of Pyrrolo[3,2-b]quinoxaline-derivatives as Kinase Inhibitors.
    Unzue A, Jessen-Trefzer C, Spiliotopoulos D, Gaudio E, Tarantelli C, Dong J, Zhao H, Leibl J, Zahler S, Bernasconi E, Sartori G, Cascione L, Bertoni F, Sledz P, Caflisch A, Nevado C
    RSC Medicinal Chemistry, 2020,11, 665-675.
  6. Four phosphates at one blow: access to pentaphosphorylated magic spot nucleotides and their analysis by capillary electrophoresis.
    Haas TM, Qiu D, Häner M, Angebauer L, Ripp A, Singh J, Koch HG, Jessen-Trefzer C, Jessen HJ.
    Journal of Organic Chemistry, 2020 Jun 5. doi: 10.1021/acs.joc.0c00841.
  7. Detection and Characterization of a Mycobacterial L-Arabinofuranose ABC Transporter Identified with a Rapid Lipoproteomics Protocol.
    Li M, Muller C, Frohlich K, Gorka O, Zhang L, Gross O, Schilling O, Einsle O, Jessen-Trefzer C*
    Cell Chemical Biology, 2019; 26 (6): 852-862.e6
    *corresponding author
  8. Trehalose Conjugation Enhances Toxicity of Photosensitizers against Mycobacteria
    Dutta A, Choudhary E, Wang X, Záhorszka M, Forbak M, Lohner P, Jessen H, Agarwal N, Korduláková J, Jessen-Trefzer C*
    ACS Central Science, 2019; 5 (4): 644–650.
    *corresponding author
  9. Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-beta-D-ribofuranose 2’-oxidase DprE1.
    Trefzer C, Skovierova H, Buroni S, Bobovska A, Nenci S, Molteni E, Pojer F, Pasca MR, Makarov V, Cole ST, Riccardi G, Mikusova K, Johnsson K
    Journal of the American Chemical Society, 2012; 134 (2): 912-915.
  10. Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-beta-D-ribose 2’-epimerase DprE1 of Mycobacterium tuberculosis.
    Trefzer C, Rengifo-Gonzalez M, Hinner MJ, Schneider P, Makarov V, Cole ST, Johnsson K
    Journal of the American Chemical Society, 2010; 132 (39):13663-13665.