Centre for Biological Signalling Studies

Dr. Claudia Jessen-Trefzer

Dr. Claudia Jessen-Trefzer

Pharmaceutical Biology and Biotechnology, University of Freiburg

+49 761 203 8381

10 selected publications:

  1. The two-component locus MSMEG_0244/0246 together with MSMEG_0243 affects biofilm assembly in M. smegmatis correlating with changes in phosphatidylinositol mannosides acylation.
    Li M, Gašparovič H, Weng X, Chen S, Korduláková J*, Jessen-Trefzer C*
    Frontiers in Microbiology, 2020, doi: 10.3389/fmicb.2020.570606.
    *corresponding author
  2. Understanding the Mechanism of Action of Pyrrolo[3,2-b]quinoxaline-derivatives as Kinase Inhibitors.
    Unzue A, Jessen-Trefzer C, Spiliotopoulos D, Gaudio E, Tarantelli C, Dong J, Zhao H, Leibl J, Zahler S, Bernasconi E, Sartori G, Cascione L, Bertoni F, Sledz P, Caflisch A, Nevado C
    RSC Medicinal Chemistry, 2020,11, 665-675.
  3. Four phosphates at one blow: access to pentaphosphorylated magic spot nucleotides and their analysis by capillary electrophoresis.
    Haas TM, Qiu D, Häner M, Angebauer L, Ripp A, Singh J, Koch HG, Jessen-Trefzer C, Jessen HJ.
    Journal of Organic Chemistry, 2020 Jun 5. doi: 10.1021/acs.joc.0c00841.
  4. Detection and Characterization of a Mycobacterial L-Arabinofuranose ABC Transporter Identified with a Rapid Lipoproteomics Protocol.
    Li M, Muller C, Frohlich K, Gorka O, Zhang L, Gross O, Schilling O, Einsle O, Jessen-Trefzer C*
    Cell Chemical Biology, 2019; 26 (6): 852-862.e6
    *corresponding author
  5. Trehalose Conjugation Enhances Toxicity of Photosensitizers against Mycobacteria
    Dutta A, Choudhary E, Wang X, Záhorszka M, Forbak M, Lohner P, Jessen H, Agarwal N, Korduláková J, Jessen-Trefzer C*
    ACS Central Science, 2019; 5 (4): 644–650.
    *corresponding author
  6. Magic spot nucleotides: tunable target-specific chemoenzymatic synthesis.
    Haas TM, Ebensperger P, Eisenbeis VB, Nopper C, Durr T, Jork N, Steck N, Jessen-Trefzer C, Jessen HJ
    Chemical Communication, 2019; 55, 5339-5342.
  7. New WS9326A Derivatives and One New Annimycin Derivative with Antimalarial Activity are Produced by Streptomyces asterosporus DSM 41452 and Its Mutant.
    Zhang S, Zhu J, Zechel DL, Jessen-Trefzer C, Eastman RT, Paululat T, Bechthold A
    ChemBioChem, 2018; 19 (3): 272-279.
  8. Wide Distribution of Foxicin Biosynthetic Gene Clusters in Streptomyces Strains An Unusual Secondary Metabolite with Various Properties.
    Greule A, Marolt M, Deubel D, Peintner I, Zhang S, Jessen-Trefzer C, De Ford C, Burschel S, Li SM, Friedrich T, Merfort I, Ludeke S, Bisel P, Muller M, Paululat T, Bechthold A
    Frontiers in Microbiology, 2017; 8: 221-221.
  9. Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-beta-D-ribofuranose 2’-oxidase DprE1.
    Trefzer C, Skovierova H, Buroni S, Bobovska A, Nenci S, Molteni E, Pojer F, Pasca MR, Makarov V, Cole ST, Riccardi G, Mikusova K, Johnsson K
    Journal of the American Chemical Society, 2012; 134 (2): 912-915.
  10. Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-beta-D-ribose 2’-epimerase DprE1 of Mycobacterium tuberculosis.
    Trefzer C, Rengifo-Gonzalez M, Hinner MJ, Schneider P, Makarov V, Cole ST, Johnsson K
    Journal of the American Chemical Society, 2010; 132 (39):13663-13665.