BIOSS-A

Membranes and protein–lipid interactions in signalling
BIOSS-B

Oncogenic signalling
BIOSS-C

Re-building & biotechnology
BIOSS

From Analysis
to Synthesis
Publications
2022
- Viral suppressor of RNA silencing in vascular plants also interferes with the development of the bryophyte Physcomitrella patens.
Marttinen EM, Lehtonen MT, van Gessel N, Reski R, Valkonen JPT.
Plant Cell Environ. 2022 Jan;45(1):220-235. - Monitoring checkpoints of metabolism and protein biogenesis in mitochondria by Phos-tag technology.
Walter C, Marada A, Meisinger C.
J Proteomics. 2022 Feb 10;252:104430.
2021
- Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors.
Dennerlein S, Poerschke S, Oeljeklaus S, Wang C, Richter-Dennerlein R, Sattmann J, Bauermeister D, Hanitsch E, Stoldt S, Langer T, Jakobs S, Warscheid B, Rehling P.
Elife. 2021 Dec 31;10:e68213. - The EpiDiverse Plant Epigenome-Wide Association Studies (EWAS) Pipeline.
Can SN, Nunn A, Galanti D, Langenberger D, Becker C, Volmer K, Heer K, Opgenoorth L, Fernandez-Pozo N, Rensing SA.
Epigenomes. 2021 May 4;5(2):12. - Oligosarcomas, IDH-mutant are distinct and aggressive.
Suwala AK, Felix M, Friedel D, Stichel D, Schrimpf D, Hinz F, Hewer E, Schweizer L, Dohmen H, Pohl U, Staszewski O, Korshunov A, Stein M, Wongsurawat T, Cheunsuacchon P, Sathornsumetee S, Koelsche C, Turner C, Le Rhun E, Mühlebner A, Schucht P, Özduman K, Ono T, Shimizu H, Prinz M, Acker T, Herold-Mende C, Kessler T, Wick W, Capper D, Wesseling P, Sahm F, von Deimling A, Hartmann C, Reuss DE.
Acta Neuropathol. 2021 Dec 30. Online ahead of print. - Screening for Optimal Liposome Preparation Conditions by Using Dual Centrifugation and Time-Resolved Fluorescence Measurements.
Koehler JK, Schnur J, Heerklotz H, Massing U.
Pharmaceutics. 2021 Nov 30;13(12):2046. - Editorial: Plant Phytochromes: From Structure to Signaling and Beyond.
Viczián A, Klose C, Hiltbrunner A, Nagy F.
Front Plant Sci. 2021 Dec 9;12:811379. - The role of AUX1 during lateral root development in the domestication of the model C4 grass Setaria italica.
Tang S, Shahriari M, Xiang J, Pasternak T, Igolkina A, Aminizade S, Zhi H, Gao Y, Roodbarkelari F, Sui Y, Jia G, Wu C, Zhang L, Zhao L, Li X, Meshcheryakov G, Samsonova M, Diao X, Palme K, Teale W.
J Exp Bot. 2021 Dec 23 Online ahead of print. - Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts.
Corrales E, Levit-Zerdoun E, Metzger P, Kowar S, Ku M, Brummer T, Boerries M.
Cell Commun Signal. 2021 Dec 20;19(1):123. - Stimulated Raman histology in the neurosurgical workflow of a major European neurosurgical center - part A.
Neidert N, Straehle J, Erny D, Sacalean V, El Rahal A, Steybe D, Schmelzeisen R, Vlachos A, Reinacher PC, Coenen VA, Mizaikoff B, Heiland DH, Prinz M, Beck J, Schnell O.
Neurosurg Rev. 2021 Dec 16. Online ahead of print. - From shape to contents: heterogeneity of CNS glial cells.
Chhatbar C, Prinz M.
Acta Neuropathol. 2021 Dec 15. Online ahead of print. - Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo.
Spohr C, Poggio T, Andrieux G, Schönberger K, Cabezas-Wallscheid N, Boerries M, Halbach S, Illert AL, Brummer T.
Leukemia. 2021 Dec 13. Online ahead of print. - finDr: A web server for in silico D-peptide ligand identification.
Engel H, Guischard F, Krause F, Nandy J, Kaas P, Höfflin N, Köhn M, Kilb N, Voigt K, Wolf S, Aslan T, Baezner F, Hahne S, Ruckes C, Weygant J, Zinina A, Akmeriç EB, Antwi EB, Dombrovskij D, Franke P, Lesch KL, Vesper N, Weis D, Gensch N, Di Ventura B, Öztürk MA.
Synth Syst Biotechnol. 2021 Nov 23;6(4):402-413. - Neuropathological interpretation of stimulated Raman histology images of brain and spine tumors: part B.
Straehle J, Erny D, Neidert N, Heiland DH, El Rahal A, Sacalean V, Steybe D, Schmelzeisen R, Vlachos A, Mizaikoff B, Reinacher PC, Coenen VA, Prinz M, Beck J, Schnell O.
Neurosurg Rev. 2021 Dec 10. Online ahead of print. - Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker properties.
Lan C, Stulz A, Barthes NPF, Lauw S, Salavei P, Jung M, Heerklotz H, Ulbrich MH.
Nanoscale. 2021 Dec 16;13(48):20692-20702. - Evaluating microglial phenotypes using single-cell technologies.
Sankowski R, Monaco G, Prinz M.
Trends Neurosci. 2021 Dec 3. Online ahead of print. - Transcriptome-wide in vivo mapping of cleavage sites for the compact cyanobacterial ribonuclease E reveals insights into its function and substrate recognition.
Hoffmann UA, Heyl F, Rogh SN, Wallner T, Backofen R, Hess WR, Steglich C, Wilde A.
Nucleic Acids Res. 2021 Dec 16;49(22):13075-13091. - Kinase Inhibition as Treatment for Acute and Chronic Graft-Versus-Host Disease.
Braun LM, Zeiser R.
Front Immunol. 2021 Nov 17;12:760199. - Small molecules mediate cellular reprogramming across two kingdoms.
Welsch R, Touraev A, Palme K.
J Exp Bot. 2021 Dec 4;72(22):7645-7647. - Biobridge: An Outlook on Translational Bioinks for 3D Bioprinting.
Gu Y, Forget A, Shastri VP.
Adv Sci (Weinh). 2021 Dec 3:e2103469. - Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications.
Rigano A, Ehmsen S, Öztürk SU, Ryan J, Balashov A, Hammer M, Kirli K, Boehm U, Brown CM, Bellve K, Chambers JJ, Cosolo A, Coleman RA, Faklaris O, Fogarty KE, Guilbert T, Hamacher AB, Itano MS, Keeley DP, Kunis S, Lacoste J, Laude A, Ma WY, Marcello M, Montero-Llopis P, Nelson G, Nitschke R, Pimentel JA, Weidtkamp-Peters S, Park PJ, Alver BH, Grunwald D, Strambio-De-Castillia C.
Nat Methods. 2021 Dec;18(12):1489-1495. - Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model.
Hammer M, Huisman M, Rigano A, Boehm U, Chambers JJ, Gaudreault N, North AJ, Pimentel JA, Sudar D, Bajcsy P, Brown CM, Corbett AD, Faklaris O, Lacoste J, Laude A, Nelson G, Nitschke R, Farzam F, Smith CS, Grunwald D, Strambio-De-Castillia C.
Nat Methods. 2021 Dec;18(12):1427-1440. - Reversible Shielding and Immobilization of Liposomes and Viral Vectors by Tailored Antibody-Ligand Interactions.
Thomas OS, Rebmann B, Tonn M, Schirmeister IC, Wehrle S, Becker J, Zea Jimenez GJ, Hook S, Jäger S, Klenzendorf M, Laskowski M, Kaier A, Pütz G, Zurbriggen MD, Weber W, Hörner M, Wagner HJ.
Small. 2021 Dec 3:e2105157. - SMAD4 mutations do not preclude epithelial-mesenchymal transition in colorectal cancer.
Frey P, Devisme A, Rose K, Schrempp M, Freihen V, Andrieux G, Boerries M, Hecht A.
Oncogene. 2021 Dec 3. Online ahead of print. - Towards non-blind optical tweezing by finding 3D refractive index changes through off-focus interferometric tracking.
Landenberger B, Yatish, Rohrbach A.
Nat Commun. 2021 Nov 26;12(1):6922. - Methods of In Situ Quantitative Root Biology.
Pasternak T, Pérez-Pérez JM.
Plants (Basel). 2021 Nov 6;10(11):2399. - Next- and Third-Generation Sequencing Outperforms Culture-Based Methods in the Diagnosis of Ascitic Fluid Bacterial Infections of ICU Patients.
Goelz H, Wetzel S, Mehrbarzin N, Utzolino S, Häcker G, Badr MT.
Cells. 2021 Nov 18;10(11):3226. - The Two Sweet Sides of Janus Lectin Drive Crosslinking of Liposomes to Cancer Cells and Material Uptake.
Siukstaite L, Rosato F, Mitrovic A, Müller PF, Kraus K, Notova S, Imberty A, Römer W.
Toxins (Basel). 2021 Nov 9;13(11):792. - Microglia contribute to the propagation of Aβ into unaffected brain tissue.
d'Errico P, Ziegler-Waldkirch S, Aires V, Hoffmann P, Mezö C, Erny D, Monasor LS, Liebscher S, Ravi VM, Joseph K, Schnell O, Kierdorf K, Staszewski O, Tahirovic S, Prinz M, Meyer-Luehmann M.
Nat Neurosci. 2021 Nov 22. Online ahead of print. - Editorial: Cytoskeletal Regulation of Immune Response.
Kumari S, Schamel WW, Alarcon B.
Front Cell Dev Biol. 2021 Nov 4;9:791327. - Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Morgenstern M, Peikert CD, Lübbert P, Suppanz I, Klemm C, Alka O, Steiert C, Naumenko N, Schendzielorz A, Melchionda L, Mühlhäuser WWD, Knapp B, Busch JD, Stiller SB, Dannenmaier S, Lindau C, Licheva M, Eickhorst C, Galbusera R, Zerbes RM, Ryan MT, Kraft C, Kozjak-Pavlovic V, Drepper F, Dennerlein S, Oeljeklaus S, Pfanner N, Wiedemann N, Warscheid B.
Cell Metab. 2021 Dec 7;33(12):2464-2483.e18. - Pharmacokinetic study of the novel phosphocholine derivative 3-dibutylaminopropylphosphonic acid by LC-MS coupling.
Kather MG, Zeller J, Plattner D, Breit B, Kreuzaler S, Krippner G, Peter K, Eisenhardt SU, Kammerer B.
J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Dec 1;1186:122998. - Pre-existing immunity and vaccine history determine hemagglutinin-specific CD4 T cell and IgG response following seasonal influenza vaccination.
Wild K, Smits M, Killmer S, Strohmeier S, Neumann-Haefelin C, Bengsch B, Krammer F, Schwemmle M, Hofmann M, Thimme R, Zoldan K, Boettler T.
Nat Commun. 2021 Nov 18;12(1):6720. - Proteome biology of primary colorectal carcinoma and corresponding liver metastases.
Fahrner M, Bronsert P, Fichtner-Feigl S, Jud A, Schilling O.
Neoplasia. 2021 Dec;23(12):1240-1251. - Morpholinos meet mitochondria: Targeting organellar gene expression.
Rampelt H, Pfanner N.
Cell. 2021 Nov 11;184(23):5693-5695. - The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics.
Kollewe A, Chubanov V, Tseung FT, Correia L, Schmidt E, Rössig A, Zierler S, Haupt A, Müller CS, Bildl W, Schulte U, Nicke A, Fakler B, Gudermann T.
Elife. 2021 Nov 12;10:e68544. - Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy.
Kettwig M, Ternka K, Wendland K, Krüger DM, Zampar S, Schob C, Franz J, Aich A, Winkler A, Sakib MS, Kaurani L, Epple R, Werner HB, Hakroush S, Kitz J, Prinz M, Bartok E, Hartmann G, Schröder S, Rehling P, Henneke M, Boretius S, Alia A, Wirths O, Fischer A, Stadelmann C, Nessler S, Gärtner J.
Nat Commun. 2021 Nov 11;12(1):6530. - Ift88, but not Kif3a, is required for establishment of the periciliary membrane compartment.
Kotsis F, Janusch H, Li Y, Viau A, Epting D, Kramer-Zucker A, Walz G, Nitschke R, Lorentzen E, Ganner A, Neumann-Haefelin E, Kuehn EW, Boehlke C.
Biochem Biophys Res Commun. 2021 Dec 20;584:19-25. - 46 The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML.
Charlet A, Kappenstein M, Keye P, Kläsener K, Endres C, Poggio T, Gorantla SP, Kreutmair S, Sänger J, Illert AL, Miething C, Reth M, Duyster J, Rummelt C, von Bubnoff N.
Leukemia. 2021 Nov 8. Online ahead of print. - Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia.
El Khawanky N, Hughes A, Yu W, Myburgh R, Matschulla T, Taromi S, Aumann K, Clarson J, Vinnakota JM, Shoumariyeh K, Miething C, Lopez AF, Brown MP, Duyster J, Hein L, Manz MG, Hughes TP, White DL, Yong ASM, Zeiser R.
Nat Commun. 2021 Nov 8;12(1):6436. - Host Blood Gene Signatures Can Detect the Progression to Severe and Cerebral Malaria.
Omar M, Marchionni L, Häcker G, Badr MT.
Front Cell Infect Microbiol. 2021 Oct 22;11:743616. - 3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels.
Govindasamy N, Long H, Jeong HW, Raman R, Özcifci B, Probst S, Arnold SJ, Riehemann K, Ranga A, Adams RH, Trappmann B, Bedzhov I.
Dev Cell. 2021 Dec 6;56(23):3276-3287.e8. - A small and highly sensitive red/far-red optogenetic switch for applications in mammals.
Zhou Y, Kong D, Wang X, Yu G, Wu X, Guan N, Weber W, Ye H.
Nat Biotechnol. 2021 Oct 4. Online ahead of print. - Cardiomyocyte-specific miR-100 overexpression preserves heart function under pressure overload in mice and diminishes fatty acid uptake as well as ROS production by direct suppression of Nox4 and CD36.
Smolka C, Schlösser D, Koentges C, Tarkhnishvili A, Gorka O, Pfeifer D, Bemtgen X, Asmussen A, Groß O, Diehl P, Moser M, Bode C, Bugger H, Grundmann S, Pankratz F.
FASEB J. 2021 Nov;35(11):e21956. - The Optimal Lipid Chain Length of a Membrane-Permeabilizing Lipopeptide Results From the Balance of Membrane Partitioning and Local Damage.
Steigenberger J, Verleysen Y, Geudens N, Martins JC, Heerklotz H.
Front Microbiol. 2021 Sep 14;12:669709. - Metabolic and Lipidomic Assessment of Kidney Cells Exposed to Nephrotoxic Vancomycin Dosages.
Lagies S, Pichler R, Vladimirov G, Gawron J, Bäzner F, Schreiner A, Kadena D, Plattner DA, Lienkamp SS, Kammerer B.
Int J Mol Sci. 2021 Sep 18;22(18):10111. - Quantitative proteomics identifies the universally conserved ATPase Ola1p as a positive regulator of heat shock response in Saccharomyces cerevisiae.
Dannenmaier S, Desroches Altamirano C, Schüler L, Zhang Y, Hummel J, Milanov M, Oeljeklaus S, Koch HG, Rospert S, Alberti S, Warscheid B.
J Biol Chem. 2021 Sep 24:101050. - Subcellular proteomics.
Christopher JA, Stadler C, Martin CE, Morgenstern M, Pan Y, Betsinger CN, Rattray DG, Mahdessian D, Gingras AC, Warscheid B, Lehtiö J, Cristea IM, Foster LJ, Emili A, Lilley KS.
Nat Rev Methods Primers. 2021;1:32. - Biosensor-Enabled Multiplexed On-Site Therapeutic Drug Monitoring of Antibiotics.
Ates HC, Mohsenin H, Wenzel C, Glatz RT, Wagner HJ, Bruch R, Höfflin N, Spassov S, Streicher L, Lozano-Zahonero S, Flamm B, Trittler R, Hug MJ, Köhn M, Schmidt J, Schumann S, Urban GA, Weber W, Dincer C.
Adv Mater. 2021 Sep 21:e2104555. - The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation.
Zhang P, Schlecht A, Wolf J, Boneva S, Laich Y, Koch J, Ludwig F, Boeck M, Thien A, Härdtner C, Kierdorf K, Agostini H, Schlunck G, Prinz M, Hilgendorf I, Wieghofer P, Lange C.
J Neuroinflammation. 2021 Sep 20;18(1):215. - Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling.
Schwarz JJ, Grundmann L, Kokot T, Kläsener K, Fotteler S, Medgyesi D, Köhn M, Reth M, Warscheid B.
Life Sci Alliance. 2021 Sep 15;4(11):e202101084. - Bacterial flavoprotein monooxygenase YxeK salvages toxic S-(2-succino)-adducts via oxygenolytic C-S bond cleavage.
Matthews A, Schönfelder J, Lagies S, Schleicher E, Kammerer B, Ellis HR, Stull F, Teufel R.
FEBS J. 2021 Sep 12. Online ahead of print. - Magnitude of Ubiquitination Determines the Fate of Epidermal Growth Factor Receptor Upon Ligand Stimulation.
Akimov V, Fehling-Kaschek M, Barrio-Hernandez I, Puglia M, Bunkenborg J, Nielsen MM, Timmer J, Dengjel J, Blagoev B.
J Mol Biol. 2021 Sep 8;433(21):167240. - Neuronal TNFα, Not α-Syn, Underlies PDD-Like Disease Progression in IFNβ-KO Mice. Villanueva EB, Tresse E, Liu Y, Duarte JN, Jimenez-Duran G, Ejlerskov P, Kretz O, Loreth D, Goldmann T, Prinz M, Issazadeh-Navikas S.
Ann Neurol. 2021 Sep 2. Online ahead of print. - Essential role of γ-clade RNA-dependent RNA polymerases in rice development and yield-related traits is linked to their atypical polymerase activities regulating specific genomic regions.
Jha V, Narjala A, Basu D, T N S, Pachamuthu K, Chenna S, Nair A, Shivaprasad PV.
New Phytol. 2021 Nov; 90(5):789-807 - The reaction of innate lymphoid cells in the mouse female genital tract to chlamydial infection.
Barth S, Kirschnek S, Ortmann N, Tanriver Y, Häcker G.
Infect Immun. 2021 Oct 15;89(11):e0080020. - Mitochondria as emergency landing for abandoned peroxins.
Vögtle FN, Meisinger C.
EMBO Rep. 2021 Oct 5;22(10):e53790. - Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer.
Taromi S, Firat E, Simonis A, Braun LM, Apostolova P, Elze M, Passlick B, Schumacher A, Lagies S, Frey A, Schmitt-Graeff A, Burger M, Schmittlutz K, Follo M, von Elverfeldt D, Zhu X, Kammerer B, Diederichs S, Duyster J, Manz MG, Niedermann G, Zeiser R.
Cancer Lett. 2021 Nov 1;520:385-399. - RNAProt: an efficient and feature-rich RNA binding protein binding site predictor.
Uhl M, Tran VD, Heyl F, Backofen R.
Gigascience. 2021 Aug 18;10(8):giab054. - Current tools to interrogate microglial biology.
Dumas AA, Borst K, Prinz M.
Neuron 2021 Sep 15;109(18):2805-2819. - Glycans in autophagy, endocytosis and lysosomal functions.
Reggiori F, Gabius HJ, Aureli M, Römer W, Sonnino S, Eskelinen EL.
Glycoconj J. 2021 Oct;38(5):625-647 - Structural Diversities of Lectins Binding to the Glycosphingolipid Gb3.
Siukstaite L, Imberty A, Römer W.
Front Mol Biosci. 2021 Jul 26;8:704685. - Importance of Bcl-2-family proteins in murine hematopoietic progenitor and early B cells.
Kurschat C, Metz A, Kirschnek S, Häcker G.
Cell Death Dis. 2021 Aug 11;12(8):784. - Signatures of Transcription Factor Evolution and the Secondary Gain of Red Algae Complexity.
Petroll R, Schreiber M, Finke H, Cock JM, Gould SB, Rensing SA.
Genes (Basel). 2021 Jul 9;12(7):1055. - Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine.
Oberhardt V, Luxenburger H, Kemming J, Schulien I, Ciminski K, Giese S, Csernalabics B, Lang-Meli J, Janowska I, Staniek J, Wild K, Basho K, Marinescu MS, Fuchs J, Topfstedt F, Janda A, Sogukpinar O, Hilger H, Stete K, Emmerich F, Bengsch B, Waller CF, Rieg S, Sagar, Boettler T, Zoldan K, Kochs G, Schwemmle M, Rizzi M, Thimme R, Neumann-Haefelin C, Hofmann M.
Nature. 2021 Sep;597(7875):268-273. - Flowering plant embryos: How did we end up here?
Rensing SA, Weijers D.
Plant Reprod. 2021 Dec;34(4):365-371 - Maintaining proteostasis under mechanical stress.
Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B.
EMBO Rep. 2021 Aug 4;22(8):e52507. - Editorial: How Cells Build Plants: Regulatory Mechanisms for Integrated Functioning of Plant Cells and the Whole Plant Body.
Máthé C, Nick P, Pasternak TP.
Front Plant Sci. 2021 Jul 6;12:706892. - Sulfatides are endogenous ligands for the TLR4-MD-2 complex.
Su L, Athamna M, Wang Y, Wang J, Freudenberg M, Yue T, Wang J, Moresco EMY, He H, Zor T, Beutler B.
Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2105316118. - A Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress.
Moeglin E, Desplancq D, Stoessel A, Massute C, Ranniger J, McEwen AG, Zeder-Lutz G, Oulad-Abdelghani M, Chiper M, Lafaye P, Di Ventura B, Didier P, Poterszman A, Weiss E.
Cancers (Basel). 2021 Jul 1;13(13):3317. - Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile.
Merz J, Nettesheim A, von Garlen S, Albrecht P, Saller BS, Engelmann J, Hertle L, Schäfer I, Dimanski D, König S, Karnbrock L, Bulatova K, Peikert A, Hoppe N, Hilgendorf I, von Zur Mühlen C, Wolf D, Groß O, Bode C, Zirlik A, Stachon P. - Membrane-water partitioning - Tackling the challenges of poorly soluble drugs using chaotropic co-solvents.
Naßwetter LC, Fischer M, Scheidt HA, Heerklotz H.
Biophys Chem. 2021 Oct;277:106654. - Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.
Györfi AH, Matei AE, Fuchs M, Liang C, Rigau AR, Hong X, Zhu H, Luber M, Bergmann C, Dees C, Ludolph I, Horch RE, Distler O, Wang J, Bengsch B, Schett G, Kunz M, Distler JHW.
J Exp Med. 2021 Sep 6;218(9):e20201916. - Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery.
Walter C, Marada A, Suhm T, Ernsberger R, Muders V, Kücükköse C, Sánchez-Martín P, Hu Z, Aich A, Loroch S, Solari FA, Poveda-Huertes D, Schwierzok A, Pommerening H, Matic S, Brix J, Sickmann A, Kraft C, Dengjel J, Dennerlein S, Brummer T, Vögtle FN, Meisinger C.
Nat Commun. 2021 Jul 13;12(1):4284. - Functional assessment of two variants of unknown significance in TEK by endothelium-specific expression in zebrafish embryos.
Bell LM, Holm A, Matysiak U, Driever W, Rößler J, Schanze D, Wieland I, Niemeyer CM, Zenker M, Kapp FG.
Hum Mol Genet. 2021 Dec 17;31(1):10-17 - CdrS Is a Global Transcriptional Regulator Influencing Cell Division in Haloferax volcanii.
Liao Y, Vogel V, Hauber S, Bartel J, Alkhnbashi OS, Maaß S, Schwarz TS, Backofen R, Becher D, Duggin IG, Marchfelder A.
mBio. 2021 Aug 31;12(4):e0141621. - Complex Micellization Behavior of the Polysorbates Tween 20 and Tween 80.
Knoch H, Ulbrich MH, Mittag JJ, Buske J, Garidel P, Heerklotz H.
Mol Pharm. 2021 Aug 2;18(8):3147-3157. - DTL-DephosSite: Deep Transfer Learning Based Approach to Predict Dephosphorylation Sites.
Chaudhari M, Thapa N, Ismail H, Chopade S, Caragea D, Köhn M, Newman RH, Kc DB.
Front Cell Dev Biol. 2021 Jun 24;9:662983. - PIAS2-mediated blockade of IFN-β signaling: a basis for sporadic Parkinson disease dementia.
Magalhaes J, Tresse E, Ejlerskov P, Hu E, Liu Y, Marin A, Montalant A, Satriano L, Rundsten CF, Carlsen EMM, Rydbirk R, Sharifi-Zarchi A, Andersen JB, Aznar S, Brudek T, Khodosevich K, Prinz M, Perrier JM, Sharma M, Gasser T, Issazadeh-Navikas S.
Mol Psychiatry. 2021 Jul 8. Online ahead of print. - Green Light-Controlled Gene Switch for Mammalian and Plant Cells.
Schneider N, Chatelle CV, Ochoa-Fernandez R, Zurbriggen MD, Weber W.
Methods Mol Biol. 2021;2312:89-107. - The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression.
Gentle IE, Moelter I, Badr MT, Döhner K, Lübbert M, Häcker G.
Cell Death Dis. 2021 Jul 5;12(7):675. Purinergic Signal. 2021 Sep;17(3):481-492. - DNA Repair Protein APE1 Degrades Dysfunctional Abasic mRNA in Mitochondria Affecting Oxidative Phosphorylation.
Barchiesi A, Bazzani V, Jabczynska A, Borowski LS, Oeljeklaus S, Warscheid B, Chacinska A, Szczesny RJ, Vascotto C.
J Mol Biol. 2021 Sep 3;433(18):167125. - Autophosphorylation of the KaiC-like protein ArlH inhibits oligomerization and interaction with ArlI, the motor ATPase of the archaellum.
de Sousa Machado JN, Vollmar L, Schimpf J, Chaudhury P, Kumariya R, van der Does C, Hugel T, Albers SV.
Mol Microbiol. 2021 Sep;116(3):943-956. - QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy.
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