BIOSS-A

Membranes and protein–lipid interactions in signalling
BIOSS-B

Oncogenic signalling
BIOSS-C

Re-building & biotechnology
BIOSS

From Analysis
to Synthesis
Publications
2022
- An improved organotypic cell culture system to study tissue-resident macrophages ex vivo.
Aktories P, Petry P, Glatz P, Andrieux G, Oschwald A, Botterer H, Gorka O, Erny D, Boerries M, Henneke P, Groß O, Prinz M, Kierdorf K.
Cell Rep Methods. 2022 Jul 26;2(8):100260 - MARVEL-domain containing CMTM4 affects CXCR4 trafficking.
Bona A, Seifert M, Thünauer R, Zodel K, Frew IJ, Römer W, Walz G, Yakulov TA.
Mol Biol Cell. 2022 Aug 31. Online ahead of print. - Phenotypic and functional analysis of ?? T cells in the pathogenesis of human T-cell lymphotropic virus type 1 infection.
Ruggieri M, Ducasa N, Juraske C, Polo VG, Berini C, Quiroga MF, Christopoulos P, Minguet S, Biglione M, Schamel WW.
Front Immunol. 2022 Aug 11;13:920888. - Shedding light on current trends in molecular optogenetics.
Fischer AAM, Kramer MM, Radziwill G, Weber W.
Curr Opin Chem Biol. 2022 Aug 18;70:102196. - Impact of older age in patients receiving atezolizumab and bevacizumab for hepatocellular carcinoma.
Vithayathil M, D'Alessio A, Fulgenzi CAM, Nishida N, Schönlein M, von Felden J, Schulze K, Wege H, Saeed A, Wietharn B, Hildebrand H, Wu L, Ang C, Marron TU, Weinmann A, Galle PR, Bettinger D, Bengsch B, Vogel A, Balcar L, Scheiner B, Lee PC, Huang YH, Amara S, Muzaffar M, Naqash AR, Cammarota A, Personeni N, Pressiani T, Pinter M, Cortellini A, Kudo M, Rimassa L, Pinato DJ, Sharma R.
Liver Int. 2022 Aug 20. Online ahead of print. - Anaplastic ganglioglioma - a diagnosis comprising several distinct tumour types.
Reinhardt A, Pfister K, Schrimpf D, Stichel D, Sahm F, Reuss DE, Capper D, Wefers AK, Ebrahimi A, Sill M, Felsberg J, Reifenberger G, Becker A, Prinz M, Staszewski O, Hartmann C, Schittenhelm J, Gramatzki D, Weller M, Olar A, Rushing EJ, Bergmann M, Farrell MA, Blümcke I, Coras R, Beckervordersandforth J, Kim SH, Rogerio F, Dimova PS, Niehusmann P, Unterberg A, Platten M, Pfister SM, Wick W, Herold-Mende C, von Deimling A.
Neuropathol Appl Neurobiol. 2022 Aug 17. Online ahead of print. - Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction.
Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Bandi SR, Arampatzi P, Krammer T, DiFabion N, Dietrich O, Arias-Loza AP, Prinz M, Mack M, Schlepckow K, Haass C, Silvestre JS, Zernecke A, Saliba AE, Cochain C.
Cardiovasc Res. 2022 Aug 11. Online ahead of print. - BlotIt-Optimal alignment of Western blot and qPCR experiments.
Kemmer S, Bang S, Rosenblatt M, Timmer J, Kaschek D.
PLoS One. 2022 Aug 10;17(8):e0264295. - COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation.
Reinscheid M, Luxenburger H, Karl V, Graeser A, Giese S, Ciminski K, Reeg DB, Oberhardt V, Roehlen N, Lang-Meli J, Heim K, Gross N, Baum C, Rieg S, Speer C, Emmerich F, Breisinger S, Steinmann D, Bengsch B, Boettler T, Kochs G, Schwemmle M, Thimme R, Neumann-Haefelin C, Hofmann M.
Nat Commun. 2022 Aug 8;13(1):4631 - Complex electrostatic effects on the selectivity of membrane-permeabilizing cyclic lipopeptides.
Steigenberger J, Verleysen Y, Geudens N, Madder A, Martins JC, Heerklotz H.
Biophys J. 2022 Aug 3. Online ahead of print. - A root phloem pole cell atlas reveals common transcriptional states in protophloem-adjacent cells.
Otero S, Gildea I, Roszak P, Lu Y, Di Vittori V, Bourdon M, Kalmbach L, Blob B, Heo JO, Peruzzo F, Laux T, Fernie AR, Tavares H, Helariutta Y.
Nat Plants. 2022 Aug;8(8):954-970. - 3D Printed Solutions for Spheroid Engineering and Cancer Research.
Butelmann T, Gu Y, Li A, Tribukait-Riemenschneider F, Hoffmann J, Molazem A, Jaeger E, Pellegrini D, Forget A, Shastri VP.
Int J Mol Sci. 2022 Jul 25;23(15):8188. - Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling.
Gehttps://pubmed.ncbi.nlm.nih.gov/35859176/ssler S, Guthmann C, Schuler V, Lilienkamp M, Walz G, Yakulov TA.
Int J Mol Sci. 2022 Jul 17;23(14):7870. - Seed-induced A? deposition alters neuronal function and impairs olfaction in a mouse model of Alzheimer's disease.
Ziegler-Waldkirch S, Friesen M, Loreth D, Sauer JF, Kemna S, Hilse A, Erny D, Helm C, D Errico P, Prinz M, Bartos M, Meyer-Luehmann M.
Mol Psychiatry. 2022 Jul 22. Online ahead of print. - Clock genes rescue nphp mutations in zebrafish.
Kayser N, Zaiser F, Veenstra AC, Wang H, Göcmen B, Eckert P, Franz H, Köttgen A, Walz G, Yakulov TA.
Hum Mol Genet. 2022 Jul 21. Online ahead of print. - ADAR1 averts fatal type I interferon induction by ZBP1.
Jiao H, Wachsmuth L, Wolf S, Lohmann J, Nagata M, Kaya GG, Oikonomou N, Kondylis V, Rogg M, Diebold M, Tröder SE, Zevnik B, Prinz M, Schell C, Young GR, Kassiotis G, Pasparakis M.
Nature. 2022 Jul;607(7920):776-783. - Comparative transcriptomics identifies candidate genes involved in the evolutionary transition from dehiscent to indehiscent fruits in Lepidium (Brassicaceae).
Gramzow L, Klupsch K, Fernández-Pozo N, Hölzer M, Marz M, Rensing SA, Theißen G.
BMC Plant Biol. 2022 Jul 14;22(1):340 - Designing electrochemical microfluidic multiplexed biosensors for on-site applications.
Glatz RT, Ates HC, Mohsenin H, Weber W, Dincer C. >
Anal Bioanal Chem. 2022 Sep;414(22):6531-6540. - Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia.
Grüninger PK, Uhl F, Herzog H, Gentile G, Andrade-Martinez M, Schmidt T, Han K, Morgens DW, Bassik MC, Cleary ML, Gorka O, Zeiser R, Groß O, Duque-Afonso J.
Cancer Gene Ther. 2022 Jul 6. Online ahead of print. - Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic D, Hörtenhuber M, Balwierz PJ, Zehnder T, Mukarram AK, Nepal C, Várnai C, Hadzhiev Y, Jimenez-Gonzalez A, Li N, Wragg J, D'Orazio FM, Relic D, Pachkov M, Díaz N, Hernández-Rodríguez B, Chen Z, Stoiber M, Dong M, Stevens I, Ross SE, Eagle A, Martin R, Obasaju O, Rastegar S, McGarvey AC, Kopp W, Chambers E, Wang D, Kim HR, Acemel RD, Naranjo S, Lapinski M, Chong V, Mathavan S, Peers B, Sauka-Spengler T, Vingron M, Carninci P, Ohler U, Lacadie SA, Burgess SM, Winata C, van Eeden F, Vaquerizas JM, Gómez-Skarmeta JL, Onichtchouk D, Brown BJ, Bogdanovic O, van Nimwegen E, Westerfield M, Wardle FC, Daub CO, Lenhard B, Müller F.
Nat Genet. 2022 Jul;54(7):1037-1050. - Therapy response of glucocorticoid-refractory acute GVHD of the lower intestinal tract.
Biavasco F, Ihorst G, Wäsch R, Wehr C, Bertz H, Finke J, Zeiser R.
Bone Marrow Transplant. 2022 Jun 29. Online ahead of print. - B cells expressing IgM B cell receptors of HIV-1 neutralizing antibodies discriminate antigen affinities by sensing binding association rates.
Hossain MA, Anasti K, Watts B, Cronin K, Derking R, Groschel B, Kane AP, Edwards RJ, Easterhoff D, Zhang J, Rountree W, Ortiz Y, Saunders K, Schief WR, Sanders RW, Verkoczy L, Reth M, Alam SM.
Cell Rep. 2022 Jun 28;39(13):111021. - High-dimensional profiling reveals Tc17 cell enrichment in active Crohn's disease and identifies a potentially targetable signature.
Globig AM, Hipp AV, Otto-Mora P, Heeg M, Mayer LS, Ehl S, Schwacha H, Bewtra M, Tomov V, Thimme R, Hasselblatt P, Bengsch B.
Nat Commun. 2022 Jun 27;13(1):3688. - Editorial on Translational Research in Graft-Versus-Host Disease (GVHD) and Graft-Versus-Tumor (GVT) Effect After Allogeneic Hematopoietic Cell Transplantation.
Czech M, Zeiser R, Toubai T.
Front Immunol. 2022 Jun 8;13:948720. - Therapeutic significance of ARID1A mutation in bladder cancer.
Conde M, Frew IJ.
Neoplasia. 2022 Sep;31:100814. - The greening ashore.
Schreiber M, Rensing SA, Gould SB.
Trends Plant Sci. 2022 Sep;27(9):847-857. - Exhaustion of CD39-Expressing CD8+ T Cells in Crohn's Disease Is Linked to Clinical Outcome.
Globig AM, Mayer LS, Heeg M, Andrieux G, Ku M, Otto-Mora P, Hipp AV, Zoldan K, Pattekar A, Rana N, Schell C, Boerries M, Hofmann M, Neumann-Haefelin C, Kuellmer A, Schmidt A, Boettler T, Tomov V, Thimme R, Hasselblatt P, Bengsch B.
Gastroenterology. 2022 Jun 20:S0016-5085(22)00663-1. - In-Depth Characterization of a Re-Engineered Cholera Toxin Manufacturing Process Using Growth-Decoupled Production in Escherichia coli.
Danielewicz N, Dai W, Rosato F, Webb ME, Striedner G, Römer W, Turnbull WB, Mairhofer J.
Toxins (Basel). 2022 Jun 8;14(6):396. - Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells.
Zhang YW, Mess J, Aizarani N, Mishra P, Johnson C, Romero-Mulero MC, Rettkowski J, Schönberger K, Obier N, Jäcklein K, Woessner NM, Lalioti ME, Velasco-Hernandez T, Sikora K, Wäsch R, Lehnertz B, Sauvageau G, Manke T, Menendez P, Walter SG, Minguet S, Laurenti E, Günther S, Grün D, Cabezas-Wallscheid N.
Nat Cell Biol. 2022 Jul;24(7):1038-1048. - Experimental Characterization of In Silico Red-Shift-Predicted iLOVL470T/Q489K and iLOVV392K/F410V/A426S Mutants.
Wehler P, Armbruster D, Günter A, Schleicher E, Di Ventura B, Öztürk MA.
ACS Omega. 2022 Jun 1;7(23):19555-19560. - Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders.
Hook G, Reinheckel T, Ni J, Wu Z, Kindy M, Peters C, Hook V.
Pharmacol Rev. 2022 Jul;74(3):600-629. - Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma.
Ravi VM, Will P, Kueckelhaus J, Sun N, Joseph K, Salié H, Vollmer L, Kuliesiute U, von Ehr J, Benotmane JK, Neidert N, Follo M, Scherer F, Goeldner JM, Behringer SP, Franco P, Khiat M, Zhang J, Hofmann UG, Fung C, Ricklefs FL, Lamszus K, Boerries M, Ku M, Beck J, Sankowski R, Schwabenland M, Prinz M, Schüller U, Killmer S, Bengsch B, Walch AK, Delev D, Schnell O, Heiland DH.
Cancer Cell. 2022 Jun 13;40(6):639-655.e13. - Histone Deacetylase 6 Inhibitor JS28 Prevents Pathological Gene Expression in Cardiac Myocytes.
Ngo V, Fleischmann BK, Jung M, Hein L, Lother A.
J Am Heart Assoc. 2022 Jun 21;11(12):e025857. - PLDMS: Phosphopeptide Library Dephosphorylation Followed by Mass Spectrometry Analysis to Determine the Specificity of Phosphatases for Dephosphorylation Site Sequences.
Kokot T, Hoermann B, Helm D, Chojnacki JE, Savitski MM, Köhn M.
Methods Mol Biol. 2022;2499:43-64. - GM-CSF suppresses antioxidant signaling and drives IL-1? secretion through NRF2 downregulation.
Di Carlo S, Häcker G, Gentle IE.
EMBO Rep. 2022 Aug 3;23(8):e54226. - RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells.
Hölzen L, Mitschke J, Schönichen C, Hess ME, Ehrenfeld S, Boerries M, Miething C, Brummer T, Reinheckel T.
Theranostics. 2022 May 16;12(9):4348-4373. - Spatially Defined Gene Delivery into Native Cells with the Red Light-Controlled OptoAAV Technology.
Hörner M, Weber W.
Curr Protoc. 2022 Jun;2(6):e440. - Synthetic microbiology applications powered by light.
Mazraeh D, Di Ventura B.
Curr Opin Microbiol. 2022 Aug;68:102158. - Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases.
Wandera KG, Alkhnbashi OS, Bassett HVI, Mitrofanov A, Hauns S, Migur A, Backofen R, Beisel CL.
Mol Cell. 2022 Jul 21;82(14):2714-2726.e4 - Disentangling ERBB Signaling in Breast Cancer Subtypes-A Model-Based Analysis.
Kemmer S, Berdiel-Acer M, Reinz E, Sonntag J, Tarade N, Bernhardt S, Fehling-Kaschek M, Hasmann M, Korf U, Wiemann S, Timmer J. Cancers (Basel). 2022 May 12;14(10):2379. - A set point in the selection of the ??TCR T cell repertoire imposed by pre-TCR signaling strength.
Bovolenta ER, García-Cuesta EM, Horndler L, Ponomarenko J, Schamel WW, Mellado M, Castro M, Abia D, van Santen HM.
Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201907119. - Distinct CD8 T Cell Populations with Differential Exhaustion Profiles Associate with Secondary Complications in Common Variable Immunodeficiency.
Klocperk A, Friedmann D, Schlaak AE, Unger S, Parackova Z, Goldacker S, Sediva A, Bengsch B, Warnatz K.
J Clin Immunol. 2022 May 19. Online ahead of print. - Determination of protoplast growth properties using quantitative single-cell tracking analysis.
Dawson J, Pandey S, Yu Q, Schaub P, Wüst F, Moradi AB, Dovzhenko O, Palme K, Welsch R.
Plant Methods. 2022 May 18;18(1):64. - Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy.
Laich Y, Wolf J, Hajdu RI, Schlecht A, Bucher F, Pauleikhoff L, Busch M, Martin G, Faatz H, Killmer S, Bengsch B, Stahl A, Lommatzsch A, Schlunck G, Agostini H, Boneva S, Lange C.
Invest Ophthalmol Vis Sci. 2022 May 2;63(5):17. - Paradoxical immunodeficiencies-When failures of innate immunity cause immunopathology.
Kolter J, Henneke P, Groß O, Kierdorf K, Prinz M, Graf L, Schwemmle M.
Eur J Immunol. 2022 May 12. Online ahead of print. - Benchmarking of analysis strategies for data-independent acquisition proteomics using a large-scale dataset comprising inter-patient heterogeneity.
Fröhlich K, Brombacher E, Fahrner M, Vogele D, Kook L, Pinter N, Bronsert P, Timme-Bronsert S, Schmidt A, Bärenfaller K, Kreutz C, Schilling O.
Nat Commun. 2022 May 12;13(1):2622. - Short peptide pharmacophores developed from protein phosphatase-1 disrupting peptides (PDPs).
Fontanillo M, Trebacz M, Reinkemeier CD, Avilés Huerta D, Uhrig U, Sehr P, Köhn M.
Bioorg Med Chem. 2022 Jul 1;65:116785. - Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B cell lymphomas.
Lopez C, Schleussner N, Bernhart SH, Kleinheinz K, Sungalee S, Sczakiel HL, Kretzmer H, Toprak UH, Glaser S, Wagener R, Ammerpohl O, Bens S, Giefing M, Sanchez JCG, Apic G, Hubschmann D, Janz M, Kreuz M, Mottok A, Muller JM, Seufert J, Hoffmann S, Korbel JO, Russell RB, Schule R, Trumper L, Klapper W, Radlwimmer B, Lichter P, Kuppers R, Schlesner M, Mathas S, Siebert R.
Haematologica. 2022 Apr 28. Online ahead of print. - Reversible, β-sheet-dependent self-assembly of the phosphoprotein phosvitin is controlled by the concentration and valency of cations.
Betschart MU, Sarem M, Shastri VP, Lüdeke S.
Phys Chem Chem Phys. 2022 May 18;24(19):11791-11800. - Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection.
Dörflinger B, Badr MT, Haimovici A, Fischer L, Vier J, Metz A, Eisele B, Bronsert P, Aumann K, Höppner J, Waguia Kontchou C, Parui I, Weber A, Kirschnek S, Häcker G.
Cell Death Differ. 2022 May 3. Online ahead of print. - The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei.
Iyer A, Niemann M, Serricchio M, Dewar CE, Oeljeklaus S, Farine L, Warscheid B, Schneider A, Bütikofer P.
PLoS Pathog. 2022 May 2;18(5):e1009717. - The Lectin LecB Induces Patches with Basolateral Characteristics at the Apical Membrane to Promote Pseudomonas aeruginosa Host Cell Invasion.
Thuenauer R, Kühn K, Guo Y, Kotsis F, Xu M, Trefzer A, Altmann S, Wehrum S, Heshmatpour N, Faust B, Landi A, Diedrich B, Dengjel J, Kuehn EW, Imberty A, Römer W.
mBio. 2022 Jun 28;13(3):e0081922. - Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer.
Taromi S, Firat E, Simonis A, Braun LM, Apostolova P, Elze M, Passlick B, Schumacher A, Lagies S, Frey A, Schmitt-Graeff A, Burger M, Schmittlutz K, Follo M, von Elverfeldt D, Zhu X, Kammerer B, Diederichs S, Duyster J, Manz MG, Niedermann G, Zeiser R.
Cancer Lett. 2022 Jul 10;538:215697. - SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA-vaccinated individuals.
Lang-Meli J, Luxenburger H, Wild K, Karl V, Oberhardt V, Salimi Alizei E, Graeser A, Reinscheid M, Roehlen N, Reeg DB, Giese S, Ciminski K, Götz V, August D, Rieg S, Waller CF, Wengenmayer T, Staudacher D, Huzly D, Bengsch B, Kochs G, Schwemmle M, Emmerich F, Boettler T, Thimme R, Hofmann M, Neumann-Haefelin C.
Nat Microbiol. 2022 May;7(5):675-679. - Benchmarking of Cph1 Mutants and DrBphP for Light-Responsive Phytochrome-Based Hydrogels with Reversibly Adjustable Mechanical Properties.
Emig R, Hoess P, Cai H, Kohl P, Peyronnet R, Weber W, Hörner M.
Adv Biol (Weinh). 2022 Jul;6(7):e2000337. - SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis.
Boettler T, Csernalabics B, Salié H, Luxenburger H, Wischer L, Salimi Alizei E, Zoldan K, Krimmel L, Bronsert P, Schwabenland M, Prinz M, Mogler C, Neumann-Haefelin C, Thimme R, Hofmann M, Bengsch B.
J Hepatol. 2022 Sep;77(3):653-659. - TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome.
Steinkellner H, Kempaiah P, Beribisky AV, Pferschy S, Etzler J, Huber A, Sarne V, Neuhaus W, Kuttke M, Bauer J, Arunachalam JP, Christodoulou J, Dressel R, Mildner A, Prinz M, Laccone F.
Int J Biol Macromol. 2022 Jun 1;209(Pt A):972-983. - Specification of CNS macrophage subsets occurs postnatally in defined niches.
Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernández-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lämmermann T, Priller J, Kierdorf K, Prinz M.
Nature. 2022 Apr;604(7907):740-748. - Inborn errors of immunity and immunodeficiencies: Antibody-mediated pathology and autoimmunity as a consequence of impaired immune reactions.
Minguet S, Nyström A, Kiritsi D, Rizzi M.
Eur J Immunol. 2022 Apr 20. Online ahead of print. - Microridge-like structures anchor motile cilia.
Yasunaga T, Wiegel J, Bergen MD, Helmstädter M, Epting D, Paolini A, Çiçek Ö, Radziwill G, Engel C, Brox T, Ronneberger O, Walentek P, Ulbrich MH, Walz G.
Nat Commun. 2022 Apr 19;13(1):2056. - patcHwork: a user-friendly pH sensitivity analysis web server for protein sequences and structures.
Schmitz M, Schultze A, Vanags R, Voigt K, Di Ventura B, Öztürk MA.
Nucleic Acids Res. 2022 Apr 19;50(W1):W560-7. - Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease.
Bray S, Dudgeon T, Skyner R, Backofen R, Grüning B, von Delft F.
J Cheminform. 2022 Apr 12;14(1):22. - Life and death of microglia: Mechanisms governing microglial states and fates.
Matsudaira T, Prinz M.
Immunol Lett. 2022 May;245:51-60. - BECLIN1 Is Essential for Podocyte Secretory Pathways Mediating VEGF Secretion and Podocyte-Endothelial Crosstalk.
Bork T, Liang W, Kretz O, Lagies S, Yamahara K, Hernando-Erhard C, Helmstädter M, Schell C, Kammerer B, Huber TB.
Int J Mol Sci. 2022 Mar 30;23(7):3825. - Microbial carbohydrate-binding toxins - From etiology to biotechnological application.
Danielewicz N, Rosato F, Dai W, Römer W, Turnbull WB, Mairhofer J.
Biotechnol Adv. 2022 Oct;59:107951. - Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak.
Waguia Kontchou C, Gentle IE, Weber A, Schoeniger A, Edlich F, Häcker G.
Cell Death Differ. 2022 Apr 9. Online ahead of print. - Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse.
Haimovici A, Höfer C, Badr MT, Bavafaye Haghighi E, Amer T, Boerries M, Bronsert P, Glavynskyi I, Fanfone D, Ichim G, Thilmany N, Weber A, Brummer T, Spohr C, Öllinger R, Janssen KP, Rad R, Häcker G.
Cell Death Dis. 2022 Apr 7;13(4):315. - T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma.
Barsch M, Salié H, Schlaak AE, Zhang Z, Hess M, Mayer LS, Tauber C, Otto-Mora P, Ohtani T, Nilsson T, Wischer L, Winkler F, Manne S, Rech A, Schmitt-Graeff A, Bronsert P, Hofmann M, Neumann-Haefelin C, Boettler T, Fichtner-Feigl S, van Boemmel F, Berg T, Rimassa L, Di Tommaso L, Saeed A, D'Alessio A, Pinato DJ, Bettinger D, Binder H, John Wherry E, Schultheiss M, Thimme R, Bengsch B.
J Hepatol. 2022 Aug;77(2):397-409. - 100 Hz ROCS microscopy correlated with fluorescence reveals cellular dynamics on different spatiotemporal scales.
Jünger F, Ruh D, Strobel D, Michiels R, Huber D, Brandel A, Madl J, Gavrilov A, Mihlan M, Daller CC, Rog-Zielinska EA, Römer W, Lämmermann T, Rohrbach A.
Nat Commun. 2022 Apr 1;13(1):1758. - The living interface between synthetic biology and biomaterial design.
Liu AP, Appel EA, Ashby PD, Baker BM, Franco E, Gu L, Haynes K, Joshi NS, Kloxin AM, Kouwer PHJ, Mittal J, Morsut L, Noireaux V, Parekh S, Schulman R, Tang SKY, Valentine MT, Vega SL, Weber W, Stephanopoulos N, Chaudhuri O.
Nat Mater. 2022 Apr;21(4):390-397. - Quinone binding sites of cyt bc complexes analysed by X-ray crystallography and cryogenic electron microscopy.
Kao WC, Hunte C.
Biochem Soc Trans. 2022 Apr 29;50(2):877-893. - CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survival.
Yogev N, Bedke T, Kobayashi Y, Brockmann L, Lukas D, Regen T, Croxford AL, Nikolav A, Hövelmeyer N, von Stebut E, Prinz M, Ubeda C, Maloy KJ, Gagliani N, Flavell RA, Waisman A, Huber S.
Cell Rep. 2022 Mar 29;38(13):110565. - Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells.
Smulski CR, Zhang L, Burek M, Teixidó Rubio A, Briem JS, Sica MP, Sevdali E, Vigolo M, Willen L, Odermatt P, Istanbullu D, Herr S, Cavallari M, Hess H, Rizzi M, Eibel H, Schneider P.
Cell Rep. 2022 Mar 29;38(13):110583. - The phytochrome interacting proteins ERF55 and ERF58 repress light-induced seed germination in Arabidopsis thaliana.
Li Z, Sheerin DJ, von Roepenack-Lahaye E, Stahl M, Hiltbrunner A.
Nat Commun. 2022 Mar 29;13(1):1656. - GVHD, IBD, and primary immunodeficiencies: The gut as a target of immunopathology resulting from impaired immunity.
Zeiser R, Warnatz K, Rosshart S, Sagar, Tanriver Y.
Eur J Immunol. 2022 Sep;52(9):1406-1418. - Deterministic Lateral Displacement Microfluidic Chip for Minicell Purification.
Sherbaz A, Konak BMK, Pezeshkpour P, Di Ventura B, Rapp BE.
Micromachines (Basel). 2022 Feb 25;13(3):365. - Spacer prioritization in CRISPR-Cas9 immunity is enabled by the leader RNA.
Liao C, Sharma S, Svensson SL, Kibe A, Weinberg Z, Alkhnbashi OS, Bischler T, Backofen R, Caliskan N, Sharma CM, Beisel CL.
Nat Microbiol. 2022 Apr;7(4):530-541. - Preliminary evidence of safety and tolerability of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma and Child-Pugh A and B cirrhosis: A real-world study.
D'Alessio A, Fulgenzi CAM, Nishida N, Schönlein M, von Felden J, Schulze K, Wege H, Gaillard VE, Saeed A, Wietharn B, Hildebrand H, Wu L, Ang C, Marron TU, Weinmann A, Galle PR, Bettinger D, Bengsch B, Vogel A, Balcar L, Scheiner B, Lee PC, Huang YH, Amara S, Muzaffar M, Naqash AR, Cammarota A, Personeni N, Pressiani T, Sharma R, Pinter M, Cortellini A, Kudo M, Rimassa L, Pinato DJ.
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