Cluster of Excellence –
University of Freiburg

Prof. Dr. Christoph Peters

Prof. Dr. Christoph Peters

Institute of Molecular Medicine and Cell Research, University of Freiburg

+49 761 203 9601


10 selected publications:

  • Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression.
    Bengsch F, Buck A, Günther SC, Seiz JR, Tacke M, Pfeifer D, von Elverfeldt D, Sevenich L, Hillebrand LE, Kern U, Sameni M, Peters C, Sloane BF, Reinheckel T (2014).
    Oncogene. 33(36):4474-8
  • Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model.
    Butinar M, Prebanda MT, Rajkovic J, Jeric B, Stoka V, Peters C, Reinheckel T, Krüger A, Turk V, Turk B, Vasiljeva O (2014).
    Oncogene. 33(26):3392-400.
  • Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment.
    Mikhaylov G, Mikac U, Magaeva AA, Itin VI, Naiden EP, Psakhye I, Babes L, Reinheckel T, Peters C, Zeiser R, Bogyo M, Turk V, Psakhye SG, Turk B, Vasiljeva O (2011).
    Nat Nanotechnol.6(9):594-602.
  • Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.
    Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Muller S, Follo M, Peters C, Reinheckel T (2011).
    Oncogene 30, 54-64.
  • Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis.
    Dennemarker J, Lohmuller T, Mayerle J, Tacke M, Lerch MM, Coussens LM, Peters, C, Reinheckel T (2010).
    Oncogene29, 1611-1621.
  • Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.
    Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Muller S, Vasiljeva O, Schwinde A, Klemm N, Deussing J, Peters C, Reinheckel T (2010).
    Proc Natl Acad Sci U S A 107, 2497-2502.
  • Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice.
    Vasiljeva O, Korovin M, Gajda M, Brodoefel H, Bojic L, Kruger A, Schurigt U, Sevenich L, Turk B, Peters C, Reinheckel T (2008).
    Oncogene27, 4191-4199.
  • Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.
    Vasiljeva O, Papazoglou A, Kruger A, Brodoefel H, Korovin M, Deussing J, Augustin N, Nielsen BS, Almholt K, Bogyo M, Peters C, Reinheckel T (2006).
    Cancer Res 66, 5242-5250.
  • The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.
    Reinheckel T, Hagemann S, Dollwet-Mack S, Martinez E, Lohmuller T, Zlatkovic G, Tobin DJ, Maas-Szabowski N, Peters C (2005).
    J Cell Sci118, 3387-3395.
  • Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
    Urbich C, Heeschen C, Aicher A, Sasaki K, Bruhl T, Farhadi MR, Vajkoczy P, Hofmann WK, Peters C, Pennacchio LA, Abolmaali ND, Chavakis E, Reinheckel T, Zeiher AM, Dimmeler S (2005).
    Nat Med 11, 206-213.