Centre for Biological Signalling Studies

A graphical user interface to design high-throughput optogenetic experiments with the optoPlate-96

Thomas OS, Hörner M, Weber W.

Nat Protoc. 2020 Jul 24. Online ahead of print.

Nat Protoc.                    online article

The application of molecular optogenetic switches for the perturbation of biological systems has resulted in unprecedented insights into cellular signaling processes. Here we present a graphical user interface to program the optoPlate-96 illumination device to enable the activation of optogenetic systems with high dose-dependeny, temporal resolution and multichromaticity. The software provides a graphical user interface for interactive configuration of the one-, two- or three-color variant of the optoPlate-96 and automatic generation of the required Arduino code.