Centre for Biological Signalling Studies

Boswellia carteri extract and 3-O-acetyl-alpha-boswellic acid suppress T cell function

Zimmermann-Klemd AM, Reinhardt JK, Nilsu T, Morath A, Falanga CM, Schamel WW, Huber R, Hamburger M, Gründemann C.

Fitoterapia. 2020;146:104694.

Fitoterapia.                 online article

In this publication we found that substances extracted from the plant Boswellia (the plant from which incense (Weihrauch) is made), can supress the activity of human T cells. An analysis of the intracellular signalling pathways in T cells indicated that the NFAT pathway was inhibited. The main relevant substance was 3-O-acetyl-alphaboswellic acid.