Lab News

Nadine Wössner and Susana Minguet publish a great review titled “LCK at the crossroad of immunodeficiency and autoimmunity: Mechanisms and

We congratulate Felix Schmidt for the defense of his great master thesis “Impact of Syndapin 2 knockdown on the T

Anna Ehret defends her PhD thesis “Illuminating T Cell Activation: New Optogenetic Tools Reveal How T Cells Integrate Serial Ligand

TCR Signalling Technologies

In the past decade our group has constantly developed new methodologies and reagents to study signaling in T and B cells. Some of these reagents are of interest to other research groups or companies. To serve the demand, we have started a small university company called TCR Signalling Technologies, where several of the reagents can be purchased. All reagents are thoroughly tested in our group before shipment.

Currently, our portfolio includes:

Cell lines (mycoplasma-free):

ZL011: 31-13.scTCRVb3

ZL011: Jurkat.scTCRVb3

ZL012: Jurkat.TCRVb3GFP

ZL021: MA5.8.mzSBP

ZL022: MA5.8.mzGFPSBP

ZL031: 2B4.shKidins

ZL031: 2B4.shScrambled

Antibodies:

PA011: anti-phospho-CD3eY

PA012: anti-phospho-CD3z   

PA021: anti-CD3z

Beads:

BE001: nitro-phenol-coupled sepharose beads

Please contact Kerstin Fehrenbach (Email: kerstin.fehrenbach(at)biologie.uni-freiburg.de) in case of interest.