Centre for Biological Signalling Studies

Immuno-Assays on Chip

Dr. Matthias Meier (IMTEK, University of Freiburg)

Within this microsystems- and bioengineering project we will implement an analytic tool for cells based on immuno-fluorescence. For this we will use multilayer soft lithography methods and large-scale integration technologies to reach a systems level. Besides the well-known advantages of microfluidic technology, i.e. reduction of reagents consumption and costs, we aim for high parallel and automated experimental setups in order to run a plethora of assay variations on a single chip for hundreds of cell cultures. The chip will help to identify the ‘How Many’s’,When’s’ and ‘Where’s’ of proteins in cell signalling pathways, starting with Akt/PKB