BIOSS-A

Membranes and protein–lipid interactions in signalling
BIOSS-B

Oncogenic signalling
BIOSS-C

Re-building & biotechnology
BIOSS

From Analysis
to Synthesis
Prof. Winfried Römer

Prof. Winfried Römer
BIOSS and Institute of Biology II
hired as BIOSS Professor
+49 761 203 67500
10 selected Publications
- The Pseudomonas aeruginosa lectin LecB causes integrin internalization and inhibits epithelial wound healing.
Thuenauer R, Landi A, Trefzer A, Altmann S, Wehrum S, Eierhoff T, Diedrich B, Dengjel J, Nyström A, Imberty A, Römer W (2020).
mBio. 11(2): e03260-19 - A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on the host cells.
Galle JN, Fechtner T, Eierhoff T, Römer W, Hegemann JH (2019).
Nat Commun. 10(1): 4644 - Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins.
Wilhelm I, Levit-Zerdoun E, Jakob J, Villringer S, Frensch M, Übelhart R, Landi A, Müller P, Imberty A, Thuenauer R, Claudinon J, Jumaa H, Reth M, Eibel H, Hobeika E, Römer W (2019).
Sci Signal. 12(571): eaao7194 - A lipid zipper triggers bacterial invasion.
Eierhoff T*, Bastian B, Thuenauer R, Madl J, Audfray A, Aigal S, Juillot S, Rydell GE, Müller S, de Bentzmann S, Imberty A, Fleck C*, Römer W* (2014).
Proc. Natl. Acad. Sci. 111(35): 12895-900 * corresponding author - Membrane Deformation by Neolectins with Engineered Glycolipid Binding Sites.
Arnaud J, Tröndle K, Claudinon J, Audfray A, Varrot A, Römer W*, Imberty A* (2014).
Angew. Chem. Int. Ed. 53(35): 9267-70 * corresponding author - Novel LecA Ligand Identified from Glycan Array Inhibits Host Cell Invasion by Pseudomonas aeruginosa.
Novoa A, Eierhoff T, Topin J, Varrot A, Barluenga S, Imberty A*, Römer W*, Winssinger N* (2014).
Angew. Chem. Int. Ed. 53(34): 8885-9 * corresponding author - Actin dynamics drive membrane reorganization and scission in clathrin-independent endocytosis.
Römer W*, Pontani L, Sorre B, Rentero C, Berland L, Chambon V, Lamaze C, Bassereau P, Sykes C, Gaus K, Johannes L* (2010).
Cell. 140(4): 540-53 * corresponding author - Shiga toxins - from cell biology to biomedical applications.
Johannes L, Römer W (2010).
Nat Rev Microbiol. 8(2):105-16 - GM1 structure determines SV40-induced membrane invagination and infection.
Ewers H*, Römer W*, Smith AE, Bacia K, Dmitrieff S, Chai W, Mancini R, Kartenbeck J, Chambon V, Berland L, Oppenheim A, Schwarzmann G, Feizi T, Schwille P, Sens P, Helenius A, Johannes L (2010).
Nat Cell Biol. 12(1):11-8 * contributed equally - Shiga toxin induces tubular membrane invaginations for its uptake into cells.
Römer W, Berland L, Chambon V, Gaus K, Windschiegl B, Tenza D, Aly MR, Fraisier V, Florent J-C, Perrais D, Lamaze C, Raposo G, Steinem C, Sens P, Bassereau P, Johannes L (2007).
Nature. 450:670-675