Cluster of Excellence –
University of Freiburg

Structure and mechanism of membrane signaling complexes

Prof. Dr. Carola Hunte (Institute of Biochemistry and Molecular Biology, ZBMZ and BIOSS Centre for Biological Signalling Studies)

Cellular signaling is mediated through protein assemblies of different complexity that operate as integrated circuits. We aim for X-ray structures of membrane signaling complexes to provide insights in the unknown organization principles of these assemblies and for a better understanding of the mechanisms of signal transduction at and across membranes. This knowledge will pave the way to challenge and control signaling processes by synthetic approaches.