Cluster of Excellence –
University of Freiburg

Low-volume label-free detection of molecule-protein interactions on microarrays by imaging reflectometric interferometry

Burger J, Rath C, Woehrle J, Meyer PA, Ben Ammar N, Kilb N, Brandstetter T, Pröll F, Proll G, Urban G, Roth G.

SLAS Technol. 2017;22(4):437-446

J Lab Autom.          online article

We developed a device for imaging label-free real-time analysis of binding events on surfaces. We describe the device and its functional parts in detail. On several examples we tested the binding events and compared it with state of the art instruments like Biacore.