Cluster of Excellence –
University of Freiburg

Prof. Dr. Nikolaus Pfanner

Prof. Dr. Nikolaus Pfanner

Institute of Biochemistry and Molecular Biology, University of Freiburg
 

+49 761 203 5224

10 selected publications: 

  • Molecular architecture of the active mitochondrial protein gate.
    Shiota T, Imai K, Qiu J, Hewitt VL, Tan K, Shen HH, Sakiyama N, Fukasawa Y, Hayat S, Kamiya M, Elofsson A, Tomii K, Horton P, Wiedemann N, Pfanner N, Lithgow T, Endo T (2015).
    Science 349, 1544-1548.
  • Cell cycle-dependent regulation of mitochondrial preprotein translocase.
    Harbauer AB, Opalinska M, Gerbeth C, Herman JS, Rao S, Schönfisch B, Guiard B, Schmidt O, Pfanner N*, Meisinger C* (2014).
    Science 346, 1109-1113.
  • Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation.
    Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S, Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N*, Wiedemann N*, Becker T (2013).
    Cell 154, 596-608. 
  • Regulation of mitochondrial protein import by cytosolic kinases.
    Schmidt O, Harbauer AB, Rao S, Eyrich B, Zahedi RP, Stojanovski D, Schönfisch B, Guiard B, Sickmann A, Pfanner N*, Meisinger C* (2011).
    Cell 144, 227-239.
  • Importing mitochondrial proteins: machineries and mechanisms.
    Chacinska A, Koehler CM, Milenkovic D, Lithgow T, Pfanner N* (2009).
    Cell 138, 628-644.
  • Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability.
    Vögtle FN, Wortelkamp S, Zahedi RP, Becker D, Leidhold C, Gevaert K, Kellermann J, Voos W, Sickmann A*, Pfanner N*, Meisinger C (2009).
    Cell 139, 428-439.
  • Dissecting membrane insertion of mitochondrial b-barrel proteins.
    Kutik S, Stojanovski D, Becker L, Becker T, Meinecke M, Krüger V, Prinz C, Meisinger C, Guiard B, Wagner R, Pfanner N*, Wiedemann N (2008).
    Cell 132, 1011-1024.
  • Tim50 maintains the permeability barrier of the mitochondrial inner membrane.
    Meinecke M, Wagner R*, Kovermann P, Guiard B, Mick DU, Hutu DP, Voos W, Truscott KN, Chacinska A, Pfanner N*, Rehling P (2006).
    Science 312, 1523-1526.
  • Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.
    Chacinska A, Lind M, Frazier AE, Dudek J, Meisinger C, Geissler A, Sickmann A, Meyer HE, Truscott KN, Guiard B, Pfanner N*, Rehling P* (2005).
    Cell 120, 817-829.
  • Protein insertion into the mitochondrial inner membrane by a twin-pore translocase.
    Rehling P, Model K, Brandner K, Kovermann P, Sickmann A, Meyer H, Kühlbrandt W, Wagner R, Truscott KN, Pfanner N* (2003).
    Science 299, 1747-1751.

*corresponding author