Cluster of Excellence –
University of Freiburg

Prof. Dr. Maja Köhn

Prof. Dr. Maja Köhn

BIOSS and Institute of Biology III, University of Freiburg
 

+49 761 203 67900

Open position: Technical Assistant

 

DEPOD – the dephosphorylation database

 

10 selected publications:

  • PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position.
    Luján P, Varsano G, Rubio T, Hennrich ML, Sachsenheimer T, Gálvez-Santisteban M, Martín-Belmonte F, Gavin AC, Brügger B, Köhn M.
    J Cell Sci. 2016 Nov 1;129(21):4130-4142.
  • Synthesis of Highly Selective Submicromolar Microcystin-Based Inhibitors of Protein Phosphatase (PP)2A over PP1.
    Fontanillo M, Zemskov I, Häfner M, Uhrig U, Salvi F, Simon B, Wittmann V, Köhn M.
    Angew Chem Int Ed Engl. 2016 Nov 2;55(45):13985-13989
  • Approaches to Study Phosphatases.
    Fahs S, Lujan P, Köhn M.
    ACS Chem Biol. .2016 Nov 18;11(11):2944-2961.
  • The human DEPhOsphorylation database DEPOD: a 2015 update.
    Duan G, Li X, Köhn M.
    Nucleic Acids Res. 2015 Jan;43(Database issue):D531-5.
  • Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver.
    Hoeger B, Diether M, Ballester PJ, Köhn M.
    Eur J Med Chem. 2014 Dec 17;88:89-100.
  • Unnatural amino acid mutagenesis reveals dimerization as a negative regulatory mechanism of VHR's phosphatase activity.
    Pavic K, Rios P, Dzeyk K, Koehler C, Lemke EA, Köhn M.
    ACS Chem Biol. 2014 Jul 18;9(7):1451-9.
  • Development of accessible peptidic tool compounds to study the phosphatase PTP1B in intact cells.
    Meyer C, Hoeger B, Temmerman K, Tatarek-Nossol M, Pogenberg V, Bernhagen J, Wilmanns M, Kapurniotu A, Köhn M.
    ACS Chem Biol. 2014 Mar 21;9(3):769-76
  • Elucidating human phosphatase-substrate networks.
    Li X, Wilmanns M, Thornton J, Köhn M.
    Sci Signal. 2013 May 14;6(275):rs10.
  • Chemical activators of protein phosphatase-1 induce calcium release inside intact cells.
    Reither G, Chatterjee J, Beullens M, Bollen M, Schultz C, Köhn M.
    Chem Biol. 2013 Sep 19;20(9):1179-86.
  • Development of a peptide that selectively activates protein phosphatase-1 in living cells.
    Chatterjee J, Beullens M, Sukackaite R, Qian J, Lesage B, Hart DJ, Bollen M, Köhn M.
    Angew Chem Int Ed Engl. 2012 Oct 1;51(40):10054-9