Cluster of Excellence –
University of Freiburg

Prof. Dr. Gerd Walz

Prof. Dr. Gerd Walz

Department of Medicine, Renal Division, University Medical Centre Freiburg

+49 761 270 32500

10 selected publications:

  • The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells.
    Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G (2015).
    J Cell Biol. 211(5):963-73
  • Autosomal dominant polycystic kidney disease: the changing face of clinical management.
    Ong AC, Devuyst O, Knebelmann B, Walz G; ERA-EDTA Working Group for Inherited Kidney Diseases (2015).
    Lancet. 385(9981):1993-2002.
  • ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
    Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstadter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS (2013).
    Nat Genet 45(8):951-956.
  • Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension.
    Lienkamp SS, Liu K, Karner CM, Carroll TJ, Ronneberger O, Wallingford JB, Walz G (2012).
    Nat Genet 44(12):1382-1387.
  • Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease.
    Walz G, Budde K, Mannaa M, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hörl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Büchert M, May C, Gschaidmeier H, Kramer S, Eckardt KU (2010).
    N Eng J Med. 363: 830-40.
  • Inversin relays Frizzled-8 signals to promote proximal pronephros development.
    Lienkamp S, Ganner A, Boehlke C, Schmidt T, Arnold SJ, Schäfer T, Romaker D, Schuler J, Hoff S, Powelske C, Eifler A, Krönig C, Bullerkotte A, Nitschke R, Kuehn EW, Kim E, Burkhardt H, Brox T, Ronneberger O, Gloy J, Walz G (2010).
    Proc Natl Acad Sci U S A 107: 20388-93, 2010
  • Primary cilia regulate mTORC1 activity and cell size through Lkb1.
    Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, Beyer T, Janusch H, Hamann C, Godel M, Muller K, Herbst M, Hornung M, Doerken M, Kottgen M, Nitschke R, Igarashi P, Walz G, Kuehn EW (2010).
    Nat Cell Biol 12(11):1115-1122
  • Scribble links Fat1 to the Hippo signaling cascade during zebrafish pronephros development.
    Skouloudaki K, Puetz M, Simons M, Courbard JR, Hartleben B, Engel C, Moeller MJ, Schäfer T, Ramachandran H, Mlodzik M, Huber TB, Kim E, Kramer-Zucker A, Walz G (2009).
    Proc Natl Acad Sci U S A 106: 8579-84.
  • Regulation of ciliary polarity by the APC/C.
    Ganner A, Lienkamp S, Schäfer T, Romaker D, Wegierski T, Park TJ, Spreitzer S. Simons M, Gloy J, Kim E, Wallingford JB, Walz G (2009).
    Proc Natl Acad Sci U S A 106: 17799-804.
  • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways.
    Simons M, Gloy J, Ganner A, Bullerkotte A, Bashkurov M, Kronig C, Schermer B, Benzing T, Cabello OA, Jenny A, Mlodzik M, Polok B, Driever W, Obara T, Walz G (2005).
    Nat Genet. 37, 537-543.