Cluster of Excellence –
University of Freiburg

Prof. Dr. Rolf Backofen

Prof. Dr. Rolf Backofen

Faculty of Engineering, Institute for Bioinformatics
University of Freiburg

10 selected publications:

  • RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-?B pathway.
    Murakawa Y, Hinz M, Mothes J, Schuetz A, Uhl M, Wyler E, Yasuda T, Mastrobuoni G, Friedel CC, Dölken L Kempa S, Schmidt-Supprian M, Blüthgen N, Backofen R, Heinemann U, Wolf J, Scheidereit C, Landthaler M.
    Nat Commun. 2015 Jul 14;6:7367
  • Deciphering the Epigenetic Code of Cardiac Myocyte Transcription.
    Preissl S, Schwaderer M, Raulf A, Hesse M, Gruning BA, Kobele C, Backofen R, Fleischmann BK, Hein L, Gilsbach R.
    Circ Res. 2015 Aug 14;117(5):413-23.
  • Volatile signalling by sesquiterpenes from ectomycorrhizal fungi reprogrammes root architecture.
    Ditengou FA, Muller A, Rosenkranz M, Felten J, Lasok H, van Doorn MM, Legue V, Palme K, Schnitzler JP, Polle A.
    Nat Commun 2015, 6:6279.
  • GraphProt: modeling binding preferences of RNA-binding proteins.
    Maticzka D, Lange SJ, Costa F, Backofen R.
    Genome Biol 2014, 15(1):R17.
  • Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.
    Schubert D, Bode C, Kenefeck R, Hou TZ, Wing JB, Kennedy A, Bulashevska A, Petersen BS, Schaffer AA, Gruning BA et al.
    Nat Medicine 2014, 20(12):1410-1416.
  • Comparative genomics boosts target prediction for bacterial small RNAs.
    Wright PR, Richter AS, Papenfort K, Mann M, Vogel J, Hess WR, Backofen R, Georg J.
    Proc Natl Acad Sci U S A 2013, 110(37):E3487-3496.
  • Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila.
    Ilik IA, Quinn JJ, Georgiev P, Tavares-Cadete F, Maticzka D, Toscano S, Wan Y, Spitale RC, Luscombe N, Backofen R et al.
    Mol Cell 2013, 51(2):156-173.
  • Global or local? Predicting secondary structure and accessibility in mRNAs.
    Lange SJ, Maticzka D, Mohl M, Gagnon JN, Brown CM, Backofen R.
    Nucleic Acids Res 2012, 40(12):5215-5226.
  • Sequencing errors or SNPs at splice-acceptor guanines in dbSNP?
    Platzer M, Hiller M, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Huse K.
    Nat Biotechnol 2006, 24(9):1068-1070.
  • Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity.
    Hiller M, Huse K, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Platzer M.
    Nat Genet 2004, 36(12):1255-1257.