Signal-Sensing and Signal-Transducing Smart Biomaterials
Using synthetic biology tools we develop smart biomaterials that respond to external stimuli by the release of therapeutic substances. Such smart biomaterials are currently under investigation as smart drug depots for the controlled release of therapeutic proteins in animals.
- Drug-sensing hydrogels for the inducible release of biopharmaceuticals
Nat Mater. (2008) 7:800-804.
- Stimuli-responsive hydrogels drugs take control.
Nat Mater. (2008) 7:767-768
gene therapy technology-based biomaterial for the trigger-inducible release of
biopharmaceuticals in mice.
Advanced Functional Materials, DOI: 10.1002/adfm.20090237