Prof. Dr. Ralf Reski
 |
Institut für Biologie II (Pflanzenbiotechnologie), Universität Freiburg Tel: +49 761 203 6969 |
Opposing scientific mainstream I have developed the moss Physcomitrella patens to a model species for evolutionary developmental biology, systems biology, and synthetic biology. Four of my scientific achievements with this species are the first identification of a gene function in plants by gene targeting, first functional identification of a protein pivotal for division of any eukaryotic organelle, first complete genome sequence of a lower plant, and identification of a novel mechanism for eukaryotic gene regulation. Further, I am co-inventor of the Moss Bioreactor.
We are interested in the identification of novel biochemical pathways, unravelling the signalling events leading to developmental decisions and to protection against abiotic stress, and in the production of complex biopharmaceuticals in the Moss Bioreactor.
10 ausgewählte Publikationen:
- Nonflowering plants possess a unique folate-dependent phenylalanine
hydroxylase that is localized in chloroplasts.
Pribat A, Noiriel A, Morse AM, Davis JM, Fouquet R, Loizeau K, Ravanel S, Frank W, Haas R, Reski R, Bedair M, Sumner LW, Hanson AD (2010).
Plant Cell 22, 3410-3422. - The moss Physcomitrella patens contains cyclopentenones but no
jasmonates: mutations in allene oxide cyclase lead to reduced fertility and
altered sporophyte morphology.
Stumpe M, Göbel C, Faltin B, Beike AK, Hause B, Himmelsbach K, Bode J, Kramell R, Wasternack C, Frank W, Reski R, Feussner I (2010).
New Phytol. 188, 740-749. - Transcriptional control of gene expression by
microRNAs.
Khraiwesh B. Arif MA, Seumel GI, Ossowski S, Weigel D, Reski R, Frank W (2010).
Cell 140, 111-122. - Regulation of stem cell maintenance by the Polycomb
protein FIE has been conserved during land plant evolution.
Mosquna A, Katz A, Decker EL, Rensing SA, Reski R, Ohad N (2009).
Development 136, 2433-2444. - Moss (Physcomitrella
patens) GH3 proteins act in auxin homeostasis.
Ludwig-Müller J, Jülke S, Bierfreund NM, Decker EL, Reski R (2009).
New Phytol. 181, 323-338. - A PIIB-type Ca2+-ATPase is
essential for stress adaptation in Physcomitrella
patens.
Qudeimat E, Faltusz AMC, Wheeler G, Lang D, Brownlee C, Reski R, Frank W (2008).
Proc Natl Acad Sci U S A 105, 19554-19559. - Exploring plant biodiversity: the Physcomitrella
genome and beyond.
Lang, D., A.D. Zimmer, S.A. Rensing, R. Reski (2008):
Trends Plant Sci. 13, 542-549. - The Physcomitrella
genome reveals evolutionary insights into the conquest of land by plants.
Rensing SA, Lang D, Zimmer AD, Terry A, Salamov A, Shapiro H, Nishiyama T, Perroud PF, Lindquist EA, Kamisugi Y, Tanahashi T, Sakakibara K, Fujita T, Oishi K, Shin-I T, Kuroki Y, Toyoda A, Suzuki Y, Hashimoto S, Yamaguchi K, Sugano S, Kohara Y, Fujiyama A, Anterola A, Aoki S, Ashton N, Barbazuk WB, Barker E, Bennetzen JL, Blankenship R, Cho SH, Dutcher SK, Estelle M, Fawcett JA, Gundlach H, Hanada K, Heyl A, Hicks KA, Hughes J, Lohr M, Mayer K, Melkozernov A, Murata T, Nelson DR, Pils B, Prigge M, Reiss B, Renner T, Rombauts S, Rushton PJ, Sanderfoot A, Schween G, Shiu SH, Stueber K, Theodoulou FL, Tu H, Van de Peer Y, Verrier PJ, Waters E, Wood A, Yang L, Cove D, Cuming AC, Hasebe M, Lucas S, Mishler BD, Reski R, Grigoriev IV, Quatrano RS, Boore JL. (2008).
Science 319, 64-69. -
Moss bioreactors producing improved biopharmaceuticals.
Decker EL, Reski R (2007).
Curr Opin Biotechnol. 18, 393-398. - The mechanism of gene targeting in Physcomitrella
patens: homologous recombination, concatenation and multiple integration.
Kamisugi Y, Schlink K, Rensing SA, Schween G, v. Stackelberg M, Cuming AC, Reski R, Cove DJ (2006).
Nucleic Acids Res. 34, 6205-6214.