Funded by:

Publications supported by BIOSS

2010

Sparsification of RNA structure prediction including pseudo-knots

Möhl M, Salari R, Will S, Backofen R, Sahinalp SC.

Algorithms Mol Biol. 2010;5:39

DeltaA/DeltaD Regulate Multiple and Temporally Distinct Phases of Notch Signaling during Dopaminergic Neurogenesis in Zebrafish.

Mahler J, Filippi A, Driever W.

J Neurosci. 2010;30(49):16621-35

Identifiability and observability analysis for experimental design in nonlinear dynamical models.

Raue A, Becker V, Klingmüller U, Timmer J.

Chaos. 2010;20(4):045105

The moss Physcomitrella patens contains cyclopentenones but no jasmonates: mutations in allene oxide cyclase lead to reduced fertility and altered sporophyte morphology.

Stumpe M, Göbel C, Faltin B, Beike AK, Hause B, Himmelsbach K, Bode J, Kramell R, Wasternack C, Frank W, Reski R, Feussner I.

New Phytol. 2010;188(3):740-9.

Quantitative proteomics for the analysis of spatio-temporal protein dynamics during autophagy.

Zimmermann AC, Zarei M, Eiselein S, Dengjel J.

Autophagy. 2010;6(8):1009-16.

Quinone binding and catalysis.

McMillan F, Hunte C.

Biochimica et Biophysica Acta 1797 (2010), 1841.

Inversin relays Frizzled-8 signals to promote proximal pronephros development.

Lienkamp S, Ganner A, Boehlke C, Schmidt T, Arnold SJ, Schäfer T, Romaker D, Schuler J, Hoff S, Powelske C, Eifler A, Krönig C, Bullerkotte A, Nitschke R, Kuehn EW, Kim E, Burkhardt H, Brox T, Ronneberger O, Gloy J, Walz G.

Proc Natl Acad Sci U S A. 2010;107(47):20388-93.

Microscopy with self-reconstructing beams.

Fahrbach F, Simon P, Rohrbach A

Nature Photonics 4, 780-785

A line scanned light-sheet microscope with phase shaped self-reconstructing beams

Fahrbach F, Rohrbach A

Optics Express 18, 23, 24229-24244

Protein conducting nanopores.

Harsman A, Krüger V, Bartsch P, Honigmann A, Schmidt O, Rao S, Meisinger C, Wagner R.

J. Phys.: Condens. Matter 22 (2010) 454102 (21pp)

Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor

Heizmann B, Reth M, Infantino S.

Proc Natl Acad Sci U S A. 2010;107(43):18563-8

Transcription Factors ETF, E2F, and SP-1 Are Involved in Cytokine-Independent Proliferation of Murine Hepatocytes.

Zellmer S, Schmidt-Heck W, Godoy P, Weng H, Meyer C, Lehmann T, Sparna T, Schormann W, Hammad S, Kreutz C, Timmer J, von Weizsäcker F, Thürmann PA, Merfort I, Guthke R, Dooley S, Hengstler JG, Gebhardt R.

Hepatology. 2010;52(6):2127-36.

Primary cilia regulate mTORC1 activity and cell size through Lkb1.

Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, Beyer T, Janusch H, Hamann C, Gödel M, Müller K, Herbst M, Hornung M, Doerken M, Köttgen M, Nitschke R, Igarashi P, Walz G, Kuehn EW.

Nat Cell Biol. 2010;12(11):1115-22

The dissociation activation model of B cell antigen receptor triggering

Yang J, Reth M

FEBS Lett 2010;584(24):4872-7

Continuous microfluidic DNA extraction using phase-transfer magnetophoresis

Karle M, Miwa J, Czilwik G, Auwärter V, Roth G, Zengerle R, von Stetten F.

Lab Chip. 2010;10(23):3284-90

Centrifugal microfluidic system for primary amplification and secondary real-time PCR.

Focke M, Stumpf F, Roth G, Zengerle R, von Stetten F.

Lab Chip. 2010;10(23):3210-2.

Ca2+-activated K+ channels: from protein complexes to function

Berkefeld H, Fakler B, Schulte U.

Physiol Rev. 2010;90(4):1437-59.

Specialized roles for cysteine cathepsins in health and disease.

Reiser J, Adair B, Reinheckel T.

J Clin Invest. 2010;120(10):3421-31

Synthetic Gene Networks in Mammalian Cells

Weber W, Fussenegger M.

Curr Opin Biotechnol. 2010; 21(5):690-6

Raney-Platinum Film electrodes for potentially implantable glucose fuel cells. Part 1: Nickel-free glucose oxidation anodes.

Kerzenmacher S, Schroeder M, Brämer R, Zengerle R, von Stetten F.

J Power Source 195, 19, 6516-6523

Raney-platinum film electrodes for potentially implantable glucose fuel cells. Part 2: Glucose-tolerant oxygen reduction cathodes.

Kerzenmacher S, Kräling U, Schroeder M, Brämer R, Zengerle R, von Stetten F.

J Power Source 195, 19, 6524-6531

Docking Proteins

Brummer T, Schmitz-Peiffer C, Daly RJ.

FEBS J. 2010;277(21):4356-69

Oligomeric organization of the B-cell antigen receptor on resting cells

Yang J, Reth M.

Nature. 2010;467(7314):465-9

Assembly of the Mitochondrial Protein Import Channel Role of Tom5 in Two-Stage Interaction of Tom40 with the SAM Complex.

Becker T, Guiard B, Thornton N, Zufall N, Stroud DA, Wiedemann N, Pfanner N.

Mol Biol Cell. 2010;21(18):3106-13

BiP modulates the affinity of its co-chaperone ERj1 for ribosomes.

Benedix J, Lajoie P, Jaiswal H, Burgard C, Greiner M, Zimmermann R, Rospert S, Snapp EL, Dudek J.

J Biol Chem. 2010;285(47):36427-33.

Mitochondrial protein import: from proteomics to functional mechanisms.

Schmidt O, Pfanner N, Meisinger C.

Nat Rev Mol Cell Biol. 2010;11(9):655-67

α2B-Adrenoceptor Deficiency Leads to Postnatal Respiratory Failure in Mice.

Haubold M, Gilsbach R, Hein L.

J Biol Chem. 2010;285(44):34213-9

Impaired turnover of autophagolysosomes in cathepsin L deficiency.

Dennemärker J, Lohmüller T, Müller S, Aguilar SV, Tobin DJ, Peters C, Reinheckel T.

Biol Chem. 2010;391(8):913-22

N-linked glycosylation selectively regulates autonomous precursor BCR function

Ubelhart R, Bach MP, Eschbach C, Wossning T, Reth M, Jumaa H.

Nat Immunol. 2010;11(8):759-65.

Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain

Müller CS, Haupt A, Bildl W, Schindler J, Knaus HG, Meissner M, Rammner B, Striessnig J, Flockerzi V, Fakler B, Schulte U.

Proc Natl Acad Sci U S A. 2010;107(34):14950-7

Cooperation of Stop-Transfer and Conservative Sorting Mechanisms in Mitochondrial Protein Transport.

Bohnert M, Rehling P, Guiard B, Herrmann JM, Pfanner N, van der Laan M.

Curr Biol. 2010;20(13):1227-32

Adhesive bonding of microfluidic chips: influence of process parameters.

Riegger L, Strohmeier O, Faltin B, Zengerle R, Koltay P

J. Micromech. Microeng. 20 (2010) 087003

Microstructuring of polymer films for sensitive genotyping by real-time PCR on a centrifugal microfluidic platform.

Focke M, Stumpf F, Faltin B, Reith P, Bamarni D, Wadle S, Müller C, Reinecke H, Schrenzel J, Francois P, Mark D, Roth G, Zengerle R, von Stetten F.

Lab Chip. 2010;10(19):2519-26

Functional Modules and Structural Basis of Conformational Coupling in Mitochondrial Complex I

Hunte C, Zickermann V, Brandt U.

Science. 2010;329(5990):448-51

A Gene Therapy Technology-based biomaterial for the trigger-inducible release of biopharmaceuticals in mice.

Kämpf M, Christen E, Ehrbar M, Daoud-El Baba M, Charpin-El Hamri G, Fussenegger M, Weber W

Adv. Funct. Mater. 2010, 20, 2534–2538

Harmonic Filters for 3D Multi-Channel Data: Rotation Invariant Detection of Mitoses in Colorectal Cancer.

Schlachter M, Reisert M, Herz C, Schlürmann F, Lassmann S, Werner M, Burkhardt H, Ronneberger O.

IEEE Trans Med Imaging. 2010;29(8):1485-95.

Pre-storage of liquid reagents in glass ampoules for DNA extraction on a fully integrated lab-on-a-chip cartridge.

Hoffmann J, Mark D, Lutz S, Zengerle R, von Stetten F.

Lab Chip. 2010;10(11):1480-4

Lab-on-a-Foil: microfluidics on thin and flexible films.

Focke M, Kosse D, Müller C, Reinecke H, Zengerle R, von Stetten F.

Lab Chip. 2010;10(11):1365-86

Covering a broad dynamic range: Information Processing at the Eurythropoietin Receptor.

Becker V, Schilling M, Bachmann J, Baumann U, Raue A, Maiwald T, Timmer J, Klingmüller U.

Science. 2010;328(5984):1404-8.

Assembling the outer membrane.

Stroud DA, Meisinger C, Pfanner N, Wiedemann N.

Science. 2010;328(5980):831-2

Overexpression of the Arabidopsis gene UPRIGHT ROSETTE reveals a homeostatic control for indole-3-acetic acid (IAA).

Sun Y, Yang Y, Yuan Z, Müller JL, Yu C, Xu Y, Shao X, Li X, Decker EL, Reski R, Huang H.

Plant Physiol. 2010;153(3):1311-20

Carbon electrodes for direct electron transfer type laccase cathodes investigated by current density–cathode potential behavior.

Rubenwolf S, Strohmeier O, Kloke A, Kerzenmacher S, Zengerle R, von Stetten F.

Biosens Bioelectron. 2010;26(2):841-5

Control of Dpp morphogen signalling by a secreted feedback regulator.

Vuilleumier R, Springhorn A, Patterson L, Koidl S, Hammerschmidt M, Affolter M, Pyrowolakis G.

Nat Cell Biol. 201012(6):611-7

TassDB2 - A comprehensive database of subtle alternative splicing events.

Sinha R, Lenser T, Jahn N, Gausmann U, Friedel S, Szafranski K, Huse K, Rosenstiel P, Hampe J, Schuster S, Hiller M, Backofen R, Platzer M.

BMC Bioinformatics. 2010;11:216.

Residue-specific global fluorination of Candida antarctica lipase B in Pichia pastoris.

Budisa N, Wenger W, Wiltschi B.

Mol Biosyst. 2010;6(9):1630-9.

Identification and characterization of NAGNAG alternative splicing in the moss Physcomitrella patens.

Sinha R, Zimmer AD, Bolte K, Lang D, Reski R, Platzer M, Rensing SA, Backofen R.

BMC Plant Biol. 2010;10:76.

A versatile miniature bioreactor and its application to bioelectrochemistry studies.

Kloke A, Rubenwolf S, Bücking C, Gescher J, Kerzenmacher S, Zengerle R, von Stetten F.

Biosens Bioelectron. 2010;25(12):2559-65

Native GABAB receptors are heteromultimers with a family of auxiliary subunits

Schwenk J, Metz M, Zolles G, Turecek R, Fritzius T, Bildl W, Tarusawa E, Kulik A, Unger A, Ivankova K, Seddik R, Tiao JY, Rajalu M, Trojanova J, Rohde V, Gassmann M, Schulte U, Fakler B, Bettler B.

Nature. 2010;465(7295):231-5.

Differential role of Rab proteins in ciliary trafficking: Rab23 regulates Smoothened levels.

Boehlke C, Bashkurov M, Buescher A, Krick T, John AK, Nitschke R, Walz G, Kuehn EW.

J Cell Sci. 2010;123(Pt 9):1460-7

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice.

Hartleben B, Gödel M, Meyer-Schwesinger C, Liu S, Ulrich T, Köbler S, Wiech T, Grahammer F, Arnold SJ, Lindenmeyer MT, Cohen CD, Pavenstädt H, Kerjaschki D, Mizushima N, Shaw AS, Walz G, Huber TB.

J Clin Invest. 2010;120(4):1084-96.

DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs.

Patterson KI, Brummer T, Daly RJ, O'Brien PM.

Biochim Biophys Acta. 2010;1803(9):1003-12

Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice.

Sevenich L, Hagemann S, Stoeckle C, Tolosa E, Peters C, Reinheckel T.

Biochimie. 2010;92(11):1674-80

Early functional magnetic resonance imaging activations predict language outcome after stroke.

Saur D, Ronneberger O, Kümmerer D, Mader I, Weiller C, Klöppel S.

Brain. 2010;133(Pt 4):1252-64.

Dye-based coatings for hydrophobic valves and their application to polymer labs-on-a-chip.

Riegger L, Mielnik MM, Gulliksen A, Mark D, Steigert J, Lutz S, Clad M, Zengerle R, Koltay P, Hoffmann J

J. Micromech. Microeng. 20 (2010) 045021

A model organism approach: defining the role of Neph proteins as regulators of neuron.

Neumann-Haefelin E, Kramer-Zucker A, Slanchev K, Hartleben B, Noutsou F, Martin K, Wanner N, Ritter A, Gödel M, Pagel P, Fu X, Müller A, Baumeister R, Walz G, Huber TB.

Hum Mol Genet. 2010;19(12):2347-59.