Our Goals at BIOSS
Our research strategy at BIOSS is to combine modern analytical methods with synthetic approaches to analyse complex signalling pathways. Using this combined analytic-synthetic strategy, BIOSS scientists aim to gain a more detailed functional and quantitative understanding of the working principles of signalling networks. They will focus on seven major questions which are relevant to the comprehensive study of signalling study:
- Who is involved With whom are the signalling components intaractions?
- What are the results of signalling?
- How does signalling work and Where does it occur?
- When does a specific signalling event take place and How much signalling is necessary or essential for a defined response?
Signalling pathways are the result of evolutionary processes, and the research programme of BIOSS profits from the fact that the major model organisms - including bacteria, yeast, worm, fly, fish, moss, mouse, Arabidopsis, rice, and human - are well studied in Freiburg. We are building on this foundation of excellent research by pursuing a cross-species and interdisciplinary research programme comprising the two analytical areas of studying signalling processes (A) inside and (B) between cells. We also have (C) a synthetic area of research that tests analytical results and models by rebuilding the systems analysed. The area focussing on (D) technical developments and (Z) technology and services provide the essential tools for the first three areas of research.
BIOSS Area A: Intracellular Signalling Pathways
BIOSS Area B: Supracellular Signalling Systems