Funded by:

Prof. Dr. Bernd Fakler

       

Institute of Physiology II, University of Freiburg

Tel:       +49 761 203 5175

Email:   bernd.fakler@physiologie.uni-freiburg.de

homepage

 

Short CV

 

10 selected publications:

  • Native GABAB receptors are heteromultimers with a family of auxiliary subunits.
    Schwenk J, Metz M, Zolles G, Turecek R, Fritzius T, Bildl W, Tarusawa E, Kulik A, Unger A, Ivankova A, Seddik R, Tiao JY, Rajalu M, Trojanova J, Rohde V, Gassmann M, Schulte U, Fakler B, Bettler B (2010).
    Nature 465:231-235.
  • Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain.
    Müller C, Haupt A, Bildl W, Schindler J, Knaus HG, Meissner M, Rammner B, Striessnig J, Flockerzi V, Fakler B, Schulte U (2010).
    Proc Natl Acad Sci< 107:14950-14957.
  • Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA rceptors.
    Schwenk J, Harmel N, Zolles G, Bildl W, Kulik A, Heimrich B, Chisaka O, Jonas P, Schulte U, Fakler B, Klöcker N (2009). 
    Science 323, 1313-1319
  • Association with the auxiliary subunit PEX5R/Trip8b controls responsiveness of HCN channels to cAMP and adrenergic stimulation.
    Zolles G, Wenzel D, Bildl W, Schulte U, Hofmann A, Muller CS, Thumfart JO, Vlachos A, Deller T, Pfeifer A, Fleischmann BK, Roeper J, Fakler B, Klocker N (2009).
    Neuron 62:814-825.
  • BKCa-Cav channel complexes mediate rapid and localized Ca2+-activated K+ signalling.
    Berkefeld H, Sailer CA, Bildl W, Rohde V, Thumfart JO, Eble S, Klugbauer N, Reisinger E, Bischofberger J, Oliver D, Knaus HG, Schulte U, Fakler B (2006). 
    Science 314, 615-620.
  • Pacemaking by HCN channels requires interaction with phosphoinositides.
    Zolles G, Klöcker N, Wenzel D, Weisser-Thomas J, Fleischmann BK, Roeper J, Fakler B (2006).
    Neuron 52:1027-36.
  • The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.
    Schulte U, Thumfart JO, Klöcker N, Sailer CA, Bildl W, Biniossek M, Dehn D, Deller T, Eble S, Abbass K, Wangler T, Knaus HG, Fakler B (2006). 
    Neuron 49, 697-706.
  • Functional conversion between A-type und delayed rectifier K+ channels by membrane lipids.
    Oliver D, Lien CC, Soom M, Baukrowitz T, Jonas P, Fakler B (2004). 
    Science 304, 265-270.
  • Protein kinase CK2 is coassembled with small conductance Ca2+-activated K+ channels and regulates channel gating.
    Bildl W, Strassmaier T, Thurm H, Andersen J, Eble S, Oliver D, Knipper M, Mann M, Schulte U, Adelman JP, Fakler B (2004). 
    Neuron 43, 847-858.
  • Intracellular anions as the voltage sensor of prestin, the outer hair cell motor protein.
    Oliver D, He DZ, Klocker N, Ludwig J, Schulte U, Waldegger S, Ruppersberg JP, Dallos P, Fakler B (2001).
    Science 292, 2340-2343.