• BIOSS Home
• Newsroom
  • In the media
  • Press Releases
  • Videos
  • Downloads
• Events
• Research Programme
  • BIOSS Area A
  • BIOSS Area B
  • BIOSS Area C
  • BIOSS Area D
    • Pathway Assembler
    • 4-D Analyser
  • Incubator
    • Incubator Team
• Synthetic Biology
  • SynBio Research
    • Analysis through Synthesis
    • Design
  • iGEM
    • iGEM 2010
    • iGEM 2009
    • iGEM 2008
  • Social-Ethics-Implications
  • SynBio News
• Teaching
• Toolbox
• Publications
  • 2011
  • 2010
  • 2009
  • 2008
• People
• Gender + Career
  • Young Researchers
  • Open Positions
• Contact
• Imprint

Funded by:

Dr. Kathrin Thedieck

Department for Bioinformatics and Molecular Genetics, University of Freiburg Tel:     +49 7614 203 2725 Email: kathrin.thedieck@biologie.uni-freiburg.de homepage

The group of Kathrin Thedieck  analyses the TOR pathway and its role in metabolic processes by means of biochemistry, proteomics and cell biology in human cells and in the genetic model organism C. elegans.

 

Short CV

 

Publications

• A Dynamic Network Model of mTOR Signaling Reveals TSC-Independent mTORC2 Regulation.
  Dalle Pezze P*, Sonntag AG*, Thien A, Prentzell MT, Gödel M, Fischer S, Neumann-Haefelin E, Huber TB, Baumeister R, Shanley DP°, Thedieck K° (2012).
  Sci Signal 5 (217), ra25  (featured article mTOR focus issue). 
  View also the perspective by Diane C. Fingar and K. Inoki.
• A modelling-experimental approach reveals IRS dependent regulation of AMPK by Insulin.
  Sonntag AG*, Dalle Pezze P*, Shanley DP°, Thedieck K° (2012)
  FEBS Journal (2012) (Systems Biology special issue).doi: 10.1111/j.1742-4658.2012.08582.x [Epub ahead of print]
• Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis.
  Lankisch TO, Metzger J, Negm AA, Voβkuhl K, Schiffer E, Siwy J, Weismüller TJ, Schneider AS, Thedieck K, Baumeister R, Zürbig P, Weissinger EM, Manns MP, Mischak H, Wedemeyer J (2011)
  Hepatology 53(3):875-84
• Translational Control by Amino Acids and Energy.
  Kathrin Thedieck K and Michael N. Hall (2009).
  The Handbook of Cell Signaling, R. Bradshaw and E. Dennis (editors), 2^nd edition.
• Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease.
  Jiang H, Schiffer E, Song Z, Wang J, Zürbig P, Thedieck K, Moes S, Bantel H, Saal N, Jantos J, Brecht M, Jenö P, Hall MN, Hager K, Manns MP, Hecker H, Ganser A, Döhner K, Bartke A, Meissner C, Mischak H, Ju Z, Rudolph KL (2008)
  Proc Natl Acad Sci USA 105(32):11299-304.
• PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis.
  Thedieck K, Polak P, Kim ML, Molle KD, Cohen A, Jenö P, Arrieumerlou C, Hall MN (2007).
  PLoS One2(11):e1217.
• The MprF protein is required for lysinylation of phospholipids in listerial membranes and confers resistance to cationic antimicrobial peptides (CAMPs) on Listeria monocytogenes.
  Thedieck K, Hain T, Mohamed W, Tindall BJ, Nimtz M, Chakraborty T, Wehland J, Jänsch L (2006).
  Mol Microbiol 62(5):1325-39. Epub 2006 Oct 17.