Gefördert durch:

Publications supported by BIOSS

2011

 

            

Dual Function of Sdh3 in the Respiratory Chain and TIM22 Protein Translocase of the Mitochondrial Inner Membrane

Gebert N, Gebert M, Oeljeklaus S, von der Malsburg K, Stroud DA, Kulawiak B, Wirth C, Zahedi RP, Dolezal P, Wiese S, Simon O, Schulze-Specking A, Truscott KN, Sickmann A, Rehling P, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N. 

Mol Cell. 2011;44(5):811-8.


            

POPCORN functions in the auxin pathway to regulate embryonic body plan and meristem organization in Arabidopsis

Xiang D, Yang H, Venglat P, Cao Y, Wen R, Ren M, Stone S, Wang E, Wang H, Xiao W, Weijers D, Berleth T, Laux T, Selvaraj G, Datla R.

Plant Cell 2011, 23(12):4348-67.


            

Embryonic development in Arabidopsis thaliana: from the zygote division to the shoot meristem

Bosca S, Knauer S, Laux T 

Frontiers in Plant Science 2011, 2, 93 


            

Old friends form alliance against podocytes

Simons M, Huber TB.

Kidney Int. 2011;80(11):1117-9.

            

Mitochondrialer Komplex 1 - Analyser einer komplexen Maschine

Zickermann V, Hunte C, Brandt U

Biospektrum 3/2011, 278-280


            

Sensitivity analysis approaches applied to systems biology models

Zi Z 

IET Syst Biol. 2011;5(6):336


            

Emerging biomedical applications of synthetic biology

Weber W, Fussenegger M.

Nat Rev Genet. 2011; 13(1):21-35


            

Evidence for interstitial carbon in nitrogenase FeMo cofactor

Spatzal T, Aksoyoglu M, Zhang L, Andrade SL, Schleicher E, Weber S, Rees DC, Einsle O 

Science. 2011;334(6058):940


            

Drosophila CENH3 is sufficient for centromere formation

Mendiburo MJ, Padeken J, Fülöp S, Schepers A, Heun P.

Science. 2011;334(6056):686-90


            

De novo design and construction of an inducible gene expression system in mammalian cells.

Karlsson M, Weber W, Fussenegger M. 

Methods Enzymol. 2011;497:239-53.


    

Bacillus subtilis MreB Orthologs Self-Organize into Filamentous Structures underneath the Cell Membrane in a Heterologous Cell System.

Dempwolff F, Reimold C, Reth M, Graumann PL 

PLoS One. 2011;6(11):e27035.


            

Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts

Tholen S, Biniossek ML, Geßler AL, Müller S, Weißer J, Kizhakkedathu JN, Reinheckel T, Schilling O 

Biol Chem. 2011;392(11):961-971


            

Prorenin Receptor is essential for Podocyte Autophagy and Survival

Riediger F, Quack I, Qadri F, Hartleben B, Park JK, Potthoff SA, Sohn D, Sihn G, Rousselle A, Fokuhl V, Maschke U, Purfürst B, Schneider W, Rump LC, Luft FC, Dechend R, Bader M, Huber TB, Nguyen G, Muller DN.

J Am Soc Nephrol. 2011 Dec;22(12):2193-202.

            

Proteomic Identification of Protease Cleavage Sites Characterizes Prime and Non-prime Specificity of Cysteine Cathepsins B, L, and S.

Biniossek ML, Nägler DK, Becker-Pauly C, Schilling O 

J Proteome Res. 2011; 10(12):5363-73


            

Dpp signaling activity requires Pentagone to scale with tissue size in the growing Drosophila wing imaginal disc.

Hamaratoglu F, de Lachapelle AM, Pyrowolakis G, Bergmann S, Affolter M. 

PLoS Biol. 2011;9(10):e1001182


            

Mitochondrial preprotein translocase of trypanosomatids has a bacterial origin.

Pusnik M, Schmidt O, Perry AJ, Oeljeklaus S, Niemann M, Warscheid B, Lithgow T, Meisinger C, Schneider A. 

Curr Biol. 2011;21(20):1738-43.


           

Gene targeting of the cysteine peptidase cathepsin h impairs lung surfactant in mice.

Bühling F, Kouadio M, Chwieralski CE, Kern U, Hohlfeld JM, Klemm N, Friedrichs N, Roth W, Deussing JM, Peters C, Reinheckel T

PLoS One. 2011;6(10):e26247


            

Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.

Du J, Say RF, Lü W, Fuchs G, Einsle O

Nature. 2011;478(7370):534-7


            

Strategies for the Fabrication of Porous Platinum Electrodes

Kloke A, von Stetten F, Zengerle R, Kerzenmacher S 

Adv Mat 2011; 23 (43); 4976-5008  


     

Microthermoforming of microfluidic substrates by soft lithography (μTSL): optimization using design of experiments

Focke M, Kosse D, Al-Bamerni D, Lutz S, Müller C, Reinecke H, Zengerle R, von Stetten F 

J. Micromech. Microeng. 21 (2011) 115002 (11pp)


            

X-ray structure of the dimeric cytochrome bc(1) complex from the soil bacterium Paracoccus denitrificans at 2.7-Å resolution

Kleinschroth T, Castellani M, Trinh CH, Morgner N, Brutschy B, Ludwig B, Hunte C.

Biochim Biophys Acta. 2011; 1807(12):1606-15


            

Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L

Savalas LR, Gasnier B, Damme M, Lübke T, Wrocklage C, Debacker C, Jézégou A, Reinheckel T, Hasilik A, Saftig P, Schröder B 

Biochem J. 2011;439(1):113-28


            

Molecular convergence of bacterial and eukaryotic surface order.

Kaiser HJ, Surma MA, Mayer F, Levental I, Grzybek M, Klemm RW, Da Cruz S, Meisinger C, Muller V, Simons K, Lingwood D.

J Biol Chem. 2011;286(47):40631-7


         

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis.

von der Malsburg K, Müller JM, Bohnert M, Oeljeklaus S, et al 

Dev Cell. 2011;21(4):694-707


         

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival.

Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, Reinheckel T, Gu C, Huber TB, Ju W, Bitzer M, Rastaldi MP, Ruiz P, Tryggvason K, Shaw AS, Faul C, Sever S, Reiser J. 

J Clin Invest. 2011;121(10):3965-80


         

A leaky mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ-Tγδ+B+NK+ human SCID.

Gil J, Busto EM, Garcillán B, Chean C, García-Rodríguez MC, Díaz-Alderete A, Navarro J, Reiné J, Mencía A, Gurbindo D, Beléndez C, Gordillo I, Duchniewicz M, Höhne K, García-Sánchez F, Fernández-Cruz E, López-Granados E, Schamel WW, Moreno-Pelayo MA, Recio MJ, Regueiro JR. 

J Clin Invest. 2011;121(10):3872-6.


         

Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes.

Kumar R, Ferez M, Swamy M, Arechaga I, Rejas MT, Valpuesta JM, Schamel WW, Alarcon B, van Santen HM. 

Immunity. 2011;35(3):375-87.


            

Composition and topology of the endoplasmic reticulum-mitochondria encounter structure

Stroud DA, Oeljeklaus S, Wiese S, Bohnert M, Lewandrowski U, Sickmann A, Guiard B, van der Laan M, Warscheid B, Wiedemann N

J Mol Biol. 2011;413(4):743-50.


            

The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization

Keller T, Egenberger B, Gorboulev V, Bernhard F, Uzelac Z, Gorbunov D, Wirth C, Koppatz S, Dötsch V, Hunte C, Sitte HH, Koepsell H. 

J Biol Chem. 2011;286(43):37874-86.


            

Photoconversion and Nuclear Trafficking Cycles Determine Phytochrome A's Response Profile to Far-Red Light

Rausenberger J, Tscheuschler A, Nordmeier W, Wüst F, Timmer J, Schäfer E, Fleck C, Hiltbrunner A 

Cell. 2011;146(5):813-25.


            

A new vampire saga: the molecular mechanism of T cell trogocytosis

Dopfer EP, Minguet S, Schamel WW. 

Immunity. 2011;35(2):151-3.


            

Functional and Spatial Analysis of C. elegans SYG-1 and SYG-2, Orthologs of the Neph/Nephrin Cell Adhesion Module Directing Selective Synaptogenesis

Wanner N, Noutsou F, Baumeister R, Walz G, Huber TB, Neumann-Haefelin E. 

PLoS One 2011;6(8):e23598


            

N2O binding at a [4Cu:2S] copper–sulphur cluster in nitrous oxide reductase

Pomowski A, Zumft WG, Kroneck PMH, Einsle O

Nature 2011; 477(7363):234-7


            

Expansion-repression mechanism for scaling the Dpp activation gradient in Drosophila wing imaginal discs

Ben-Zvi D, Pyrowolakis G, Barkai N, Shilo BZ. 

Curr Biol. 2011; 21(16):1391-6.


            

The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins.

Becker T, Wenz LS, Krüger V, Lehmann W, Müller JM, Goroncy L, Zufall N, Lithgow T, Guiard B, Chacinska A, Wagner R, Meisinger C, Pfanner N.

J Cell Biol. 2011;194(3):387-95


            

The acidic domain of cytochrome c₁ in paracoccus denitrificans, analogous to the acidic subunits in eukaryotic bc₁ complexes, is not involved in the electron transfer reaction to its native substrate cytochrome c(552).

Castellani M, Havens J, Kleinschroth T, Millett F, Durham B, Malatesta F, Ludwig B. 

Biochim Biophys Acta. 2011;1807(11):1383-9


            

Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment

Mikhaylov G, Mikac U, Magaeva AA, Itin VI, Naiden EP, Psakhye I, Babes L, Reinheckel T, Peters C, Zeiser R, Bogyo M, Turk V, Psakhye SG, Turk B, Vasiljeva O. 

Nat Nanotechnol. 2011;6(9):594-602.


            

Quantitative Analysis of Protein Phosphorylations and Interactions by Multi-Colour IP-FCM as an Input for Kinetic Modelling of Signalling Networks

Deswal S, Schulze AK, Höfer T, Schamel WW

PLoS One. 2011;6(7):e22928


            

Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range

Bachmann J, Raue A, Schilling M, Boehm ME, Kreutz C, Kaschek D, Busch H, Gretz N, Lehmann WD, Timmer J, Klingmüller U 

Mol Syst Biol. 2011; 7:516


            

A novel MCF-10A line allowing conditional oncogene expression in 3D culture

Herr R, Wöhrle FU, Danke C, Berens C, Brummer T

Cell Commun Signal. 2011;9:17.


            

Comparison of ERLIC-TiO(2), HILIC-TiO(2), and SCX-TiO(2) for Global Phosphoproteomics Approaches.

Zarei M, Sprenger A, Metzger F, Gretzmeier C, Dengjel J.

J Proteome Res. 2011; 10(8):3474-83


            

Efficient generation of B lymphocytes by recognition of self-antigens.

Eschbach C, Bach MP, Fidler I, Pelanda R, Köhler F, Rajewsky K, Jumaa H.

Eur J Immunol. 2011;41(8):2397-403


            

A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity.

Schaechinger TJ, Gorbunov D, Halaszovich CR, Moser T, Kügler S, Fakler B, Oliver D 

EMBO J. 2011;30(14):2793-804


            

A unified approach to the helioseismic inversion problem of the solar meridiol flow from global oscillations

Schad A, Timmer J, Roth M 

The Astrophysical Journal 734:97 (8pp)


            

Heterochromatin boundaries are hotspots for de novo kinetochore formation

Olszak A, van Essen D, Pereira AJ, Diehl S, Manke T, Maiato H, Saccani S, Heun P

Nat Cell Biol 2011;13(7):799-808


   

Pentagone: patrolling BMP morphogen signaling.

Vuilleumier R, Affolter M, Pyrowolakis G.

Fly (Austin). 2011;5(3):210-4.


  

Signaling at the gate: Phosphorylation of the mitochondrial protein import machinery

Rao S, Gerbeth C, Harbauer A, Mikropoulou D, Meisinger C, Schmidt O.

Cell Cycle. 2011; 10(13):2083-90.


   

Biogenesis of mitochondrial {beta}-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex

Stroud DA, Becker T, Qiu J, Stojanovski D, Pfannschmidt S, Wirth C, Hunte C, Guiard B, Meisinger C, Pfanner N, Wiedemann N.

Mol Biol Cell. 2011; 22(16):2823-33


            

Structural Basis for the Function of Tim50 in the Mitochondrial Presequence Translocase.

Qian X, Gebert M, Höpker J, Yan M, Li J, Wiedemann N, van der Laan M, Pfanner N, Sha B. 

J Mol Biol. 2011; 411(3):513-9


            

A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis

Büttner S, Ruli D, Vögtle FN, Galluzzi L, Moitzi B, Eisenberg T, Kepp O, Habernig L, Carmona-Gutierrez D, Rockenfeller P, Laun P, Breitenbach M, Khoury C, Fröhlich KU, Rechberger G, Meisinger C, Kroemer G, Madeo F. 

EMBO J. 2011; 30(14):2779-92


            

ErbB2-associated changes in the lysosomal proteome

Nylandsted J, Becker AC, Bunkenborg J, Andersen JS, Dengjel J, Jäättelä M. 

Proteomics. 2011 Jul;11(14):2830-8


            

The BAR Domain Protein PICK1 Regulates Cell Recognition and Morphogenesis by Interacting with Neph Proteins

Höhne M, Lorscheider J, von Bardeleben A, Dufner M, Scharf MA, Gödel M, Helmstädter M, Schurek EM, Zank S, Gerke P, Kurschat C, Sivritas SH, Neumann-Haefelin E, Huber TB, Reinhardt HC, Schauss AC, Schermer B, Fischbach KF, Benzing T. 

Mol Cell Biol. 2011;31(16):3241-51


            

Ubp15p, an ubiquitin hydrolase associated with the peroxisomal export machinery.

Debelyy MO, Platta HW, Saffian D, Hensel A, Thoms S, Meyer HE, Warscheid B, Girzalsky W, Erdmann R. 

J Biol Chem. 2011, 286(32):28223-34


            

Arabidopsis WIH1 and WIH2 genes act in the transition from somatic to reproductive cell fate

Lieber D, Lora J, Schrempp S, Lenhard M, Laux T

Curr Biol. 2011; 21(12):1009-17


            

Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations

Rowh MA, Demicco A, Horowitz JE, Yin B, Yang-Iott KS, Fusello AM, Hobeika E, Reth M, Bassing CH 

Oncogene. 2011; 30(47):4757-64


            

Development of an ELISA for sensitive and specific detection of IgA autoantibodies against BP180 in pemphigoid diseases.

Csorba K, Schmidt S, Florea F, Ishii N, Hashimoto T, Hertl M, Karpati S, Bruckner-Tuderman L, Nishie W, Sitaru C. 

Orphanet J Rare Dis. 2011;6(1):31


            

Computational discovery of human coding and non-coding transcripts with conserved splice sites.

Rose D, Hiller M, Schutt K, Hackermüller J, Backofen R, Stadler PF. 

Bioinformatics. 2011;27(14):1894-1900.


            

Conditional DNA-protein interactions confer stimulus-sensing properties to biohybrid materials.

Christen E, Karlsson M, Kämpf MM, Schoenmakers R, Gübeli RJ, Wischhusen HM, Friedrich C, Fussenegger M, Weber W

Adv Func Mat 2011, 21 (15), 2861–2867


            

Strong negative feedback from Erk to Raf confers robustness to MAPK signalling

Fritsche-Guenther R, Witzel F, Sieber A, Herr R, Schmidt N, Braun S, Brummer T, Sers C, Blüthgen N 

Mol Sys Biol 2011; 7:489


            

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

Gödel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, Lu S et al

J Clin Invest. 2011;121(6):2197-209


            

Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53.

Charvet C, Wissler M, Brauns-Schubert P, Wang SJ, Tang Y, Sigloch FC, Mellert H, Brandenburg M, Lindner SE, Breit B, Green DR, McMahon SB, Borner C, Gu W, Maurer U.

Mol Cell. 2011;42(5):584-96.


            

Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression

Belting HG, Wendik B, Lunde K, Leichsenring M, Mössner M, Driever W, Onichtchouk D 

Dev Biol 2011; 356; 323–336


            

BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition.

Duy C, Hurtz C, Shojaee S, Cerchietti L, Geng H, Swaminathan S, Klemm L, Kweon SM, Nahar R, Braig M, Park E, Kim YM, Hofmann WK, Herzog S, Jumaa H, Koeffler HP, Yu JJ, Heisterkamp N, Graeber TG, Wu H, Ye BH, Melnick A, Müschen M. 

Nature. 2011;473(7347):384-8.


            

Targeting Capacity and Conservation of PreP Homologues Localization in Mitochondria of Different Species

Alikhani N, Berglund AK, Engmann T, Spånning E, Vögtle FN, Pavlov P, Meisinger C, Langer T, Glaser E 

J Mol Biol. 2011;410(3):400-10


            

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

Inoki K, Mori H, Wang J, Suzuki T, Hong S, Yoshida S, Blattner SM, Ikenoue T, Rüegg MA, Hall MN, Kwiatkowski DJ, Rastaldi MP, Huber TB, Kretzler M, Holzman LB, Wiggins RC, Guan KL.

J Clin Invest. 2011;121(6):2181-96


            

Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis

Kaller M, Liffers ST, Oeljeklaus S, Kuhlmann K, Röh S, Hoffmann R, Warscheid B, Hermeking H. 

Mol Cell Proteomics. 2011;10(8):M111.010462


                           

Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics

Zi Z, Feng Z, Chapnick DA, Dahl M, Deng D, Klipp E, Moustakas A, Liu X 

Mol Sys Biol 2011; 7:492


              

Peptide signaling in plant development.

Katsir L, Davies KA, Bergmann DC, Laux T.

Curr Biol. 2011;21(9):R356-64.


                           

The Selaginella Genome Identifies Genetic Changes Associated with the Evolution of Vascular Plants.

Banks JA, Nishiyama T, Hasebe M, Bowman JL, Gribskov M et al 

Science. 2011; 332(6032):960-3.


                           

A comparison of different automated methods for the detection of white matter lesions in MRI data.

Klöppel S, Abdulkadir A, Hadjidemetriou S, Issleib S, Frings L, Thanh TN, Mader I, Teipel SJ, Hüll M, Ronneberger O (2011).

Neuroimage 15;57(2):416-22


                           

Insecticidal toxin complex proteins from Xenorhabdus nematophilus: Structure and pore formation.

Sheets JJ, Hey TD, Fencil KJ, Burton SL, Ni W, Lang AE, Benz R, Aktories K.

J Biol Chem. 2011;286(26):22742-9.


                           

Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization.

Vögtle FN, Prinz C, Kellermann J, Lottspeich F, Pfanner N, Meisinger C.

Mol Biol Cell. 2011; 22(13):2135-43.


                           

PEX14 is required for microtubule-based peroxisome motility in human cells.

Bharti P, Schliebs W, Schievelbusch T, Neuhaus A, David C, Kock K, Herrmann C, Meyer HE, Wiese S, Warscheid B, Theiss C, Erdmann R. 

J Cell Sci. 2011;124(Pt 10):1759-68


                           

Distribution of the auxiliary GABAB receptor subunits KCTD8, 12, 12b, and 16 in the mouse brain.

Metz M, Gassmann M, Fakler B, Schaeren-Wiemers N, Bettler B.

J Comp Neurol. 2011;519(8):1435-54


                           

pH-dependent gating in a FocA formate channel.

Lü W, Du J, Wacker T, Gerbig-Smentek E, Andrade SL, Einsle O.

Science. 2011;332(6027):352-4.


                           

PI3Kβ plays a critical role in neutrophil activation by immune complexes.

LKulkarni S, Sitaru C, Jakus Z, Anderson KE, Damoulakis G, Davidson K et al 

Sci Signal. 2011;4(168):ra23


                           

Actin as target for modification by bacterial protein toxins.

Aktories K, Lang AE, Schwan C, Mannherz HG..

FEBS J. 2011;278(23):4526-43


                       

Assigning DYW-type PPR proteins to RNA editing sites in the funariid mosses Physcomitrella patens and Funaria hygrometrica.

Rüdinger M, Szövényi P, Rensing SA, Knoop V. 

Plant J. 2011;67(2):370-80.


                           

Ephrin/ephrin receptor expression during early stages of mouse inner ear development.

Saeger BM, Suhm M, Neubüser A.

Dev Dyn. 2011 Jun;240(6):1578-85


                           

Molecular diversity – the toolbox for synthetic gene switches and networks

Weber W, Fussenegger M. 

Curr Opin Chem Biol. 2011;15(3):414-20.


                           

Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.

Cin H, Meyer C, Herr R, Janzarik WG, Lambert S et al 

Acta Neuropathol. 2011;121(6):763-74


                           

B cell antigen receptor-induced activation of an IRAK4-dependent signaling pathway revealed by a MALT1-IRAK4 double knockout mouse model

Dufner A, Schamel WW. 

Cell Commun Signal. 2011;9(1):6


                           

Chronic cardiac pressure overload induces adrenal medulla hypertrophy and increased catecholamine synthesis.

Schneider J, Lother A, Hein L, Gilsbach R. 

Basic Res Cardiol. 2011;106(4):591-602


                           

Prediction and validation of promoters involved in the abscisic acid response in Physcomitrella patens

Timmerhaus G, Hanke ST, Buchta K, Rensing SA 

Mol Plant 2011, 4(4):713-29


                           

RENNSH: A Novel Alpha-helix Identification Approach for Intermediate Resolution Electron Density Maps

Ma L, Reisert M, Burkhardt H.

IEEE/ACM Trans Comput Biol Bioinform. [Epub ahead of print]


                           

The identification of phosducin as a novel candidate gene for hypertension and its role in sympathetic activation.

Broeckel U, Stoll M, Hein L.

Curr Opin Nephrol Hypertens. 2011;20(2):118-24.


                           

The bacterial SRP receptor, SecA and the ribosome use overlapping binding sites on the SecY translocon.

Kuhn P, Weiche B, Sturm L, Sommer E, Drepper F, Warscheid B, Sourjik V, Koch HG. 

Traffic. 2011;12(5):563-78.


                    

A single layer glucose fuel cell intended as power supplying coating for medical implants

loke A, Biller B, Kräling U, Kerzenmacher S, Zengerle R, von Stetten F

Fuel Cells 11, 2, 316–326


                           

Blue native polyacrylamide gel electrophoresis (BN-PAGE) for analysis of multiprotein complexes from cellular lysates

Fiala GJ, Schamel WW, Blumenthal B. 

J Vis Exp. 2011;(48)


            

Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner

Schmich K, Schlatter R, Corazza N, Sá Ferreira K, Ederer M, Brunner T, Borner C, Merfort I. 

Hepatology. 2011;53(1):282-92


                           

Transcriptional activation of Arabidopsis axis patterning genes WOX8/9 links zygote polarity to embryo development.

Ueda M, Zhang Z, Laux T. 

Dev Cell. 2011;20(2):264-70


                           

Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function

Lother A, Berger S, Gilsbach R, Rösner S, Ecke A, Barreto F, Bauersachs J, Schütz G, Hein L. 

Hypertension. 2011;57(4):746-54


                           

CNK1 and other scaffolds for Akt/FoxO signaling.

Fritz RD, Radziwill G.

Biochim Biophys Acta. 2011;1813(11):1971-7


                           

SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models

Zi, Z 

Bioinformatics. 2011;27(7):1028-9.


                           

The immunohistochemical staining pattern of Gab2 correlates with distinct stages of chronic myeloid leukemia.

Aumann K, Lassmann S, Schöpflin A, May AM, Wöhrle FU, Zeiser R, Waller CF, Hauschke D, Werner M, Brummer T.

Hum Pathol. 2011;42(5):719-26


                       

Definition and characterization of the systemic T-cell dysregulation in untreated indolent B-cell lymphoma and very early CLL

Christopoulos P, Pfeifer D, Bartholomé K, Follo M, Timmer J, Fisch P, Veelken H. 

Blood. 2011;117(14):3836-46.


                       

Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems

Tay TL, Ronneberger O, Ryu S, Nitschke R, Driever W

Nat Comm 2011;2:171


                       

The chaperone network connected to human ribosome-associated complex.

Jaiswal H, Conz C, Otto H, Wölfle T, Fitzke E, Mayer MP, Rospert S. 

Mol Cell Biol. 2011;31(6):1160-73.


 

MicroRNA534a control of BLADE-ON-PETIOLE 1 and 2 mediates juvenile-to-adult gametophyte transition in Physcomitrella patens.

Saleh O, Issman N, Seumel GI, Stav R, Samach A, Reski R, Frank W, Arazi T.

Plant J. 2011;65(4):661-74



Distinct regulatory programs establish widespread sex-specific alternative splicing in Drosophila melanogaster.

Hartmann B, Castelo R, Miñana B, Peden E, Blanchette M, Rio DC, Singh R, Valcárcel J.

RNA 2011, 17(3):453-68.


   

Microfluidics in silicon/polymer technology as a cost-efficient alternative to silicon/glass

Kalkandjiev K, Riegger L , Kosse D, Welsche M, Gutzweiler L, Zengerle R, Koltay P.

J. Micromech. Microeng. 21 (2011) 025008 (8pp)


   

Aliquoting on the centrifugal microfluidic platform based on centrifugo-pneumatic valves

Mark D, Weber P, Lutz S, Focke M, Zengerle R, von Stetten F

Microfluid Nanofluid (2011) 10:1279–1288


   

Bile Proteomic Profiles Differentiate Cholangiocarcinoma from Primary Sclerosing Cholangitis and Choledocholithiasis

Lankisch TO, Metzger J, Negm AA, Voβkuhl K, Schiffer E, Siwy J, Weismüller TJ, Schneider AS, Thedieck K, Baumeister R, Zürbig P, Weissinger EM, Manns MP, Mischak H, Wedemeyer J.

Hepatology 2011, 53, 3, 875-884



Regulation of mitochondrial protein import by cytosolic kinases.

Schmidt O, Harbauer AB, Rao S, Eyrich B, Zahedi RP, Stojanovski D, Schönfisch B, Guiard B, Sickmann A, Pfanner N, Meisinger C.

Cell. 2011;144(2):227-39.


                           

Plant Carotene Cis-Trans Isomerase CRTISO: A new member of the fadred-dependent flavoproteins catalyzing non-redox reactions.

Yu Q, Ghisla S, Hirschberg J, Mann V, Beyer P

J Biol Chem. 2011;286(10):8666-76.


                           

Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma

Eisenhardt AE, Olbrich H, Röring M, Janzarik W, Van Anh TN, Cin H, Remke M, Witt H, Korshunov A, Pfister SM, Omran H, Brummer T.

Int J Cancer. 2011, 129(9):2297-2303


   

B cell homeostasis and plasma cell homing controlled by Kruppel-like factor 2

Winkelmann R, Sandrock L, Porstner M, Roth E, Mathews M, Hobeika E, Reth M, Kahn ML, Schuh W, Jäck HM.

Proc Natl Acad Sci U S A. 2011;108(2):710-5


   

Dynamic Mathematical Modeling of IL13-Induced Signaling in Hodgkin and Primary Mediastinal B-Cell Lymphoma Allows Prediction of Therapeutic Targets

Raia V, Schilling M, Böhm M, Hahn B, Kowarsch A, Raue A, Sticht C, Bohl S, Saile M, Möller P, Gretz N, Timmer J, Theis F, Lehmann WD, Lichter P, Klingmüller U.

Cancer Res 2011; 71(3); 693–704


   

PETcofold: predicting conserved interactions and structures of two multiple alignments of RNA sequences.

Seemann SE, Richter AS, Gesell T, Backofen R, Gorodkin J.

Bioinformatics. 2011;27(2):211-9


                           

mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression.

Huber TB, Walz G, Kuehn EW. 

Kidney Int. 2011 Mar;79(5):502-11


   

Controlled counter-flow motion of magnetic bead chains rolling along microchannels

Karle M, Wöhrle J, Miwa J, Paust N, Roth G, Zengerle R, von Stetten F

Microfluid Nanofluid (2011) 10:935–939


   

Biogenesis of mitochondria: dual role of Tom7 in modulating assembly of the preprotein translocase of the outer membrane.

Becker T, Wenz LS, Thornton N, Stroud D, Meisinger C, Wiedemann N, Pfanner N.

Mol Biol. 2011;405(1):113-24.


                   

The physiological roles of phosducin: from retinal function to stress-dependent hypertension

Beetz N, Hein L.

Cell Mol Life Sci. 2011;68(4):599-612


                   

Lipase Congeners Designed by Genetic Code Engineering

Hoesl MG, Acevedo-Rocha CG, Nehring S, Royter M, Wolschner C, Wiltschi B, Budisa N, Antranikian G 

ChemCatChem 2011;3;213-221


                   

Ion channels and their molecular environments--glimpses and insights from functional proteomics

Schulte U, Müller CS, Fakler B.

Semin Cell Dev Biol. 2011;22(2):132-44


                 

Generation-biased gene expression in a bryophyte model system

Szövényi P, Rensing SA, Lang D, Wray GA, Shaw AJ. 

Mol Biol Evol. 2011 Jan;28(1):803-12


      

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice

Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Müller S, Follo M, Peters C, Reinheckel T.

Oncogene. 2011, 6;30(1):54-64.


     

Production of biologically active recombinant human factor H in Physcomitrella patens.

Büttner-Mainik A, Parsons J, Jérôme H, Hartmann A, Lamer S, Schaaf A, Schlosser A, Zipfel PF, Reski R, Decker EL.

Plant Biotechnol J. 2011;9(3):373-83


     

Mitochondrial protein import machineries and lipids: a functional connection.

Gebert N, Ryan MT, Pfanner N, Wiedemann N, Stojanovski D.

Biochim Biophys Acta. 2011 Mar;1808(3):1002-11.


                       

A potentially implantable glucose fuel cell with Raney-platinum film electrodes for improved hydrolytic and oxidative stability

Kerzenmacher S, Kräling U, Metz T, Zengerle R, von Stetten F

Journal of Power Sources 196 (2011) 1264–1272


                       

Normally-closed peristaltic micropump with re-usable actuator and disposable fluidic chip

Trenkle F, Häberle S, Zengerle R

Sensors and Actuators B 154 (2011) 137–141

 

Bühling F, Kouadio M, Chwieralski CE, Kern U, Hohlfeld JM, Klemm N, Friedrichs N, Roth W, Deussing JM, Peters C, Reinheckel T